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BBP specifications


Unique identifier OMICS_29512
Name BBP
Alternative name Brucella Bioinformatics Portal
Restrictions to use None
Database management system Oracle
Community driven No
Data access Browse
User data submission Allowed
Maintained Yes


  • person_outline Yongqun He
  • person_outline Zuoshuang Xiang

Additional information

Publication for Brucella Bioinformatics Portal

BBP citations


Analyses of Brucella Pathogenesis, Host Immunity, and Vaccine Targets using Systems Biology and Bioinformatics

PMCID: 3417401
PMID: 22919594
DOI: 10.3389/fcimb.2012.00002

[…] venty-five mutated Brucella genes were identified to be attenuated inside macrophages or HeLa cells, or in an in vivo mouse model, using a literature mining and curation system (Limix) as part of the Brucella Bioinformatics Portal (BBP; Xiang et al., ). These 75 mutated Brucella genes are essential for Brucella virulence and pathogenesis and are thus treated as Brucella virulence factors (Xiang et […]


Ontology based Brucella vaccine literature indexing and systematic analysis of gene vaccine association network

BMC Immunol
PMCID: 3180695
PMID: 21871085
DOI: 10.1186/1471-2172-12-49

[…] sponsible for causing diseases in the host. Out of the 140 Brucella genes associated with Brucella vaccines, 46 are known Brucella virulence factors based on the updated curation information from the Brucella Bioinformatics Portal (BBP; [,] (Table ). In total, 81 Brucella genes are neither known protective antigens nor virulence factors. Since these genes have been studi […]


Bioinformatics analysis of Brucella vaccines and vaccine targets using VIOLIN

Immunome Res
PMCID: 2946783
PMID: 20875156
DOI: 10.1186/1745-7580-6-S1-S5

[…] d Pathogen-host Interaction Data Integration and Analysis System (PHIDIAS, []. PHIDIAS focuses on the analysis of pathogen-host interactions. Additionally, PHIDIAS contains the Brucella Bioinformatics Portal, a web-based portal with a special emphasis on Brucella genome annotation and literature mining []. PHIDIAS and BBP, also developed in our group, integrate more than 20 […]


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BBP institution(s)
Unit for Laboratory Animal Medicine, University of Michigan Medical School, Ann Arbor, MI, USA; Inc., Blacksburg, VA, USA; Department of Microbiology and Immunology, University of Michigan Medical School, Ann Arbor, MI, USA; Bioinformatics Program, University of Michigan Medical School, Ann Arbor, MI, USA
BBP funding source(s)
Supported by the NIH-NIAID R21 grant (#1R21AI057875-01), and Dr. He's startup funding from the University of Michigan.

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