Determines linear B-cell epitopes in hepatitis C virus (HCV). Bcell-HCV is a web server that can deal with the amino acid sequences of HCV antigens. It returns the identified B-cell epitopes with location information and their prediction scores. This application is implemented using a carrier-based vector machine (SVM) with 34 informative physico-chemical properties which enables accurate identification of epitopes of HCV B cells to assist in peptide-based vaccine development.
Department and Institute of Industrial Engineering and Management, Minghsin University of Science and Technology, Hsinchu, Taiwan; Institute of Bioinformatics and Systems Biology, National Chiao Tung University, Hsinchu, Taiwan; Department of Biological Science and Technology, National Chiao Tung University, Hsinchu, Taiwan
Bcell-HCV funding source(s)
Supported by National Science Council of Taiwan under the contract number MOST-103-2221-E-009-117-, and “Center for Bioinformatics Research of Aiming for the Top University Program” of the National Chiao Tung University and Ministry of Education, Taiwan, R.O.C. for the project 104W962; by UST-UCSD International Center of Excellence in Advanced Bioengineering sponsored by the Ministry of Science and Technology with I-RiCE Program under Grant Number: MOST 103-2911-I-009-101-.