Dataset features

Specifications


Application: SNP array data analysis, aCGH data analysis
Number of samples: 8
Release date: Jul 1 2013
Last update date: Jul 1 2013
Access: Public
Dataset link Visual automated fluorescence electrophoresis provides simultaneous quality, quantity, and molecular weight spectra for genomic DNA from archived neonatal blood spots

Experimental Protocol


The Swedish Repository of DBS samples collected on Guthrie 903 cards for neonatal screening of inborn diseases provided deidentified 3mm blood spot punches. There were total of eight (8) samples representing two (2) decades; 1970s: 1975, 1976, 1977, 1978; 1980s: 1980, 1982, 1984, 1986. gDNA was extracted and whole genome amplified prior to aCGH experiments using control female reference genomic DNA. The objective was to show that large rearrangements (e.g. loss of chrX in male samples) can be detected in WGA gDNA from blood spots >30 years old.

Repositories


GEO

GSE44249

ArrayExpress

E-GEOD-44249

BioProject

PRJNA189245

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