Consists of a parsimonious charge deconvolution algorithm that produces fewer artifacts. This algorithm is well-suited to high-resolution native mass spectrometry of intact glycoproteins and protein complexes. It simplifies the utilization of native mass spectrometry for the quantitative analysis of protein and protein assemblies, and can deconvolve monomer and dimer simultaneously.
Protein Metrics, Inc., San Carlos, CA, USA; Biomolecular Mass Spectrometry and Proteomics, Bijvoet Center for Biomolecular Research and Utrecht Institute for Pharmaceutical Sciences, Science4Life, Utrecht University and Netherlands Proteomics Centre, Utrecht, The Netherlands
BernEtAl2018 funding source(s)
Supported by the European Union’s Horizon 2020 research and innovation programme under grant agreement 668036 (RELENT) and 686547 (MSMed).