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Best Alignment Normalization BAN

Applies all the variations in a variant call format (VCF) file to the reference genome to create a sample genome, and then recalls the variants by aligning this sample genome back with the reference genome. BAN is a variant normalisation method for processing VCF files. This method takes into account the equivalency of sets of variants rather than processing each variant individually. Normalisation of VCF files using BAN should provide a much stronger basis for comparing and evaluating variant calling workflows.

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BAN classification

BAN specifications

Software type:
Restrictions to use:
Programming languages:
Shell (Bash)
Command line interface
Operating system:
Computer skills:

BAN distribution


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BAN support



  • Arash Bayat <>


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School of Computer Science and Engineering, University of New South Wales, Sydney, Australia

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