Beuke specifications


Unique identifier OMICS_23438
Name Beuke
Restrictions to use None
Community driven No
Data access File download, Browse
User data submission Not allowed
Maintained Yes


  • person_outline Sven Sahle
  • person_outline Kai Breuhahn

Publication for Beuke

Beuke citation


A20/TNFAIP3 Discriminates Tumor Necrosis Factor (TNF) Induced NF κB from JNK Pathway Activation in Hepatocytes

Front Physiol
PMCID: 5572400
PMID: 28878689
DOI: 10.3389/fphys.2017.00610

[…] carcinoma (HCC) cells we decided to perform a quantitative modeling approach to test whether an established model for primary hepatocytes can be adapted to fit the data from Hepa1-6 and Hep56 cells (Beuke et al., ). The methodological assumption was that the model represented and integrated quantitative information from previous experiments. The ODE-based model was originally created to describe […]

Beuke institution(s)
Department of Modeling of Biological Processes, COS Heidelberg /BIOQUANT, Heidelberg University, Germany; Department of Microbiology and Immunobiology, Harvard Medical School, Boston, MA, USA; Institute of Pathology, University Hospital of Heidelberg, Germany; Clinic for Gastroenterology, Heinrich-Heine-University of Düsseldorf, Germany; Molecular Hepatology, Department of Medicine II, Medical Faculty at Mannheim, Heidelberg University, Germany; Institute of Molecular Immunology and Experimental Oncology, München Rechts der Isar, Technische Universität München, Germany
Beuke funding source(s)
Supported by the Virtual Liver Network of the BMBF (FKZ 0315761 + 0315730 + 0315731 + 0315764) and the Klaus Tschira Foundation; the German Research Foundation through a postdoctoral fellowship grant (SCHI 1373/1-1) and by the International Society for Advancement of Cytometry (ISAC) through an ISAC Marylou Ingram Scholar award.

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