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big-Pi predictor specifications


Unique identifier OMICS_15658
Name big-Pi predictor
Interface Web user interface
Restrictions to use None
Computer skills Basic
Stability Stable
Maintained No

Publication for big-Pi predictor

big-Pi predictor citations


A Novel Protein Elicitor BAR11 From Saccharothrix yanglingensis Hhs.015 Improves Plant Resistance to Pathogens and Interacts With Catalases as Targets

Front Microbiol
PMCID: 5900052
PMID: 29686663
DOI: 10.3389/fmicb.2018.00700

[…] cording to the genome-wide sequencing results of strain Hhs.015, we analyzed its secreted protein genes using several software of SignalPv4.1, TMHMMv2.0, DAS-TMfilter, HMMTOP, Prosite Scan, PSORT and big-PI predictor and selected some of the function-unknown putative protein genes to investigate their functions after heterologous expression. According to the disease resistance to apple canker and […]


Lipophosphoglycan 3 From Leishmania infantum chagasi Binds Heparin With Micromolar Affinity

Bioinform Biol Insights
PMCID: 5858678
PMID: 29568220
DOI: 10.1177/1177932218763363

[…] implemented in TritrypDB. The signal peptide prediction was performed using SignalP 4.1 server,, and the presence of glycosylphosphatidylinositol (GPI)-anchor regions was assessed using GPI-SOM 1.5, big-PI Predictor, and PredGPI-GPI. To predict regions with N- and O-linked glycosylation, we used the NetNGlyc 1.0 and NetOGlyc 4.0 servers, respectively. The search for domains was performed using Pf […]


An insight into the salivary gland and fat body transcriptome of Panstrongylus lignarius (Hemiptera: Heteroptera), the main vector of Chagas disease in Peru

PLoS Negl Trop Dis
PMCID: 5834209
PMID: 29462134
DOI: 10.1371/journal.pntd.0006243

[…] er of the family was additionally identified, but it is not particularly enriched in either FB or SG transcriptomes. This third member has a glycophosphatidylinositol (GPI) anchor as predicted by the big-PI Predictor site [], while the two overexpressed proteins do not, indicating they are secreted and not membrane bound. This is in accordance with the postulated evolution of secreted salivary apy […]


The unique evolutionary pattern of the Hydroxyproline rich glycoproteins superfamily in Chinese white pear (Pyrus bretschneideri)

BMC Plant Biol
PMCID: 5816549
PMID: 29454308
DOI: 10.1186/s12870-018-1252-2

[…] red. For PRPs, the PPV[X][KC] sequence was required. Blastp was used to check sequences with a threshold around 10% PAST. The SP annotations were performed by SignalP4.0 [] and the GPI predictions by big-PI Predictor [, ]. […]


Analysis of Homologs of Cry toxin Receptor Related Proteins in the Midgut of a Non Bt Target, Nilaparvata lugens (Stål) (Hemiptera: Delphacidae)

PMCID: 5804751
PMID: 29415259
DOI: 10.1093/jisesa/iex102

[…] hAPN1, 2, and 4. The GPI-anchored sites are common motifs found in Cry-associated APNs. Analysis of GPI-anchored signals of bphAPNs by using three online prediction programs (PredGPI, FragAnchor, and big-PI Predictor) suggested that only near the C-terminus of bphAPN4 is there a high probability of finding a GPI-anchored site (; ). In addition, both N- and O-glycosylation sites were predicted in f […]


Liver myofibroblasts of murine origins express mesothelin: Identification of novel rat mesothelin splice variants*

PLoS One
PMCID: 5595315
PMID: 28898276
DOI: 10.1371/journal.pone.0184499

[…] identified and assembled by single-pass automated DNA sequencing. In silico analysis of predicted amino acid sequences corresponding to rat Mesothelin splice variants was performed using open-access Big-PI Predictor, Compute pI/Mw, and SignalP 4.1 Server tools from the ExPASy Bioformatics Resources portal [], EMBOSS Stretcher (Protein Alignment) tool from the EMBL-EBI bioinformatics web and progr […]

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big-Pi predictor institution(s)
European Molecular Biology Laboratory, Heidelberg, Germany; Max-Delbrück-Centrum für Molekulare Medizin, Berlin-Buch, Germany; Research Institute of Molecular Pathology, Vienna, Austria

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