Obsolete

Evaluates the degree of presence of the C-terminal sequence signal in a query proprotein sequence based on sequence properties extracted from a learning set. big-Pi predictor allows large-scale database searches for potentially Glycosylphosphatidylinositol (GPI)-anchored protein. It predicts GPI modification sites in precursor sequences. The software integrates terms evaluating amino acid type preferences at given motif positions but also terms judging the conservation of physical properties in the query sequence which represent correlation between few or many motif positions.

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big-Pi predictor classification

big-Pi predictor specifications

Software type:
Package
Restrictions to use:
None
Stability:
Stable
Interface:
Web user interface
Computer skills:
Basic

Publications

  • (Eisenhaber et al., 1999) Prediction of potential GPI-modification sites in proprotein sequences. Journal of Molecular Biology.
    PMID: 10497036

Credits

Institution(s)

European Molecular Biology Laboratory, Heidelberg, Federal Republic of Germany; Max-Delbrück-Centrum für Molekulare Medizin, Berlin-Buch, Federal Republic of Germany; Research Institute of Molecular Pathology, Vienna, Republic of Austria

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