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BiGG Models


A completely redesigned Biochemical, Genetic and Genomic knowledge base. BiGG Models contains more than 75 high-quality, manually-curated genome-scale metabolic models. On the website, users can browse, search and visualize models. BiGG Models connects genome-scale models to genome annotations and external databases. Reaction and metabolite identifiers have been standardized across models to conform to community standards and enable rapid comparison across models. Furthermore, BiGG Models provides a comprehensive application programming interface for accessing BiGG Models with modeling and analysis tools. As a resource for highly curated, standardized and accessible models of metabolism, BiGG Models will facilitate diverse systems biology studies and support knowledge-based analysis of diverse experimental data.

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1 user review

1 user review

Marouen Ben Guebila's avatar image

Marouen Ben Guebila

A must in genome scale metabolic networks.

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BiGG Models classification

BiGG Models specifications

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BiGG Models support


  • than E. Lewis <>


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Department of Bioengineering, University of California, San Diego, La Jolla, CA, USA; Center for Bioinformatics Tuebingen (ZBIT), University of Tuebingen, Tübingen, Germany; Department of Pediatrics, University of California, San Diego, La Jolla, CA, USA; Novo Nordisk Foundation Center for Biosustainability at the University of California, San Diego, La Jolla, CA, USA

Funding source(s)

National Science Foundation Graduate Research Fellowship [DGE-1144086 to Z.A.K.]; Department of Energy [DE-SC0008701 and DE-SC0004917]; European Commission as part of a Marie Curie International Outgoing Fellowship within the EU 7th Framework Program for Research and Technological Development [EU project AMBiCon, 332020]; National Institutes of Health [R21 HD080682]; Novo Nordisk Foundation [NNF 132150-002]; Novo Nordisk Foundation provided to the Center for Biosustainability at the Technical University of Denmark

Link to literature

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