16S ribosomal RNA sequencing data analysis software tools
Marker sequencing amplifies and sequences conserved but variable genomic regions, usually hypervariable regions of the essential 16S rRNA gene. One then clusters these sequences, known as amplicons, into operational taxonomic units (OTUs). This approach can handle unknown and highly diverged populations, provided that the OTUs correspond with sufficient accuracy to relevant ecological units.
(Zhbannikov et al., 2015) MetAmp: combining amplicon data from multiple markers for OTU analysis. Bioinformatics.