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BINOCh

A package that allows biologists to carry out an analysis of nucleosome occupancy data to discover stimulus-induced transcription factor binding. BINOCh first uses histone-related ChIP-seq data to detect well-positioned nucleosomes. The second step is to find pairs of nucleosomes with center to center distances characteristic of nucleosomes flanking TF binding sites and to generate a table summarizing ChIP-seq tag counts in these regions.

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BINOCh forum

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BINOCh classification

BINOCh specifications

Software type:
Package/Module
Restrictions to use:
None
Programming languages:
Python
Computer skills:
Advanced
Stability:
Stable
Maintained:
Yes
Interface:
Command line interface
Operating system:
Unix/Linux, Mac OS
License:
BSD 2-clause “Simplified” License
Version:
1.0.0
Requirements:
Numpy

BINOCh distribution

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BINOCh support

Documentation

Credits

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Publications

Institution(s)

Department of Biostatistics and Computational Biology, Dana-Farber Cancer Institute and Harvard School of Public Health, Boston, MA, USA; Department of Medical Oncology, Dana-Farber Cancer Institute and Harvard Medical School, Boston, MA, USA

Funding source(s)

This project was funded by the National Institutes of Health (R01 HG4069).

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