BioD statistics

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Associated diseases

Associated diseases

BioD specifications


Unique identifier OMICS_20057
Name BioD
Software type Framework/Library
Interface Command line interface
Restrictions to use None
Operating system Unix/Linux
Programming languages Other
License MIT License
Computer skills Advanced
Version 0.1.0
Stability Stable
Maintained Yes



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  • person_outline Pjotr Prins <>
  • person_outline Sebastian Wilzbach <>
  • person_outline George Githinji <>

BioD in publications

PMCID: 5930771
PMID: 29720087
DOI: 10.1186/s12864-018-4700-3

[…] controls provided by the supplier were included and b2 oligonucleotides were added to each hybridization cocktail. polya controls (lys, phe, thr, dap) and hybridization controls (biob, bioc, biod and cre) were used to monitor labeling and hybridization. open-source software included within the r statistical package [] were used for the statistical analysis of the chip outputs. […]

PMCID: 5935190
PMID: 29750019
DOI: 10.2147/DDDT.S144240

[…] m. tuberculosis., biotin is an essential cofactor required for fatty acid metabolism, amino acid biosynthesis and gluconeogenesis. m. tuberculosis harbors four necessary genes, namely, biof, bioa, biod and biob, which encode enzymes required for the biosynthesis of biotin from pimeloyl-coa., the second step of biotin biosynthesis pathway is catalyzed by 7,8-diaminopelargonic acid synthase […]

PMCID: 5919458
PMID: 29698445
DOI: 10.1371/journal.pone.0196349

[…] (mio). biotin is a vitaminic cofactor that transfers co2 as well as c-2 units, and its imidazole moiety is formed enzymatically by action of the dethiobiotin synthetase [ec:] (biod) enzyme. quite significantly, both creatinine and mio are imidazole molecules formed non-enzymatically. creatinine is formed via the spontaneous cyclization of creatine-phosphate []. […]

PMCID: 5843645
PMID: 29520052
DOI: 10.1038/s41467-018-03408-4

[…] 3′ ivt express kit (affymetrix; santa clara, ca). 7.5 µg of biotinylated crna were fragmented and placed in a hybridization cocktail containing four biotinylated hybridization controls (biob, bioc, biod, and cre) as recommended by the manufacturer. samples were hybridized to an identical lot of affymetrix genechip hg-u133 plus 2.0 for 16 h at 45 °c., steps for washing and sa-pe staining […]

PMCID: 5827029
PMID: 29483542
DOI: 10.1038/s41598-018-21926-5

[…] reactions involved in fatty acid and carbohydrate metabolism. the two important enzymes involved in the biotin synthesis, the bioa-encoded 7,8-diaminopelargonic acid synthase and the biod-encoded dethiobiotin synthase, separately catalyzes the first and second step of biotin biosynthesis, were both down-regulated in vwb-1, making it disabled in biotin biosynthesis. hence, […]

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