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BioGPS specifications


Unique identifier OMICS_03291
Name BioGPS
Restrictions to use None
Data access File download, Browse, Application programming interface
Maintained Yes


  • Primates
    • Homo sapiens


  • person_outline Chunlei Wu

Publications for BioGPS

BioGPS citations


JMJD1B Demethylates H4R3me2s and H3K9me2 to Facilitate Gene Expression for Development of Hematopoietic Stem and Progenitor Cells

Cell Rep
PMCID: 5933860
PMID: 29641999
DOI: 10.1016/j.celrep.2018.03.051

[…] Human JMJD1B is highly expressed in hematopoietic cells, retinal tissue, and pineal glands (, suggesting that it plays a role in development and/or maintenance of proper cellular functions in these cells. Similar to human hematopoietic cells, mouse HSPCs also expressed elevated JM […]


RGS7 is recurrently mutated in melanoma and promotes migration and invasion of human cancer cells

Sci Rep
PMCID: 5766496
PMID: 29330521
DOI: 10.1038/s41598-017-18851-4

[…] tary Fig. , both cell types express RGS7 to various degrees. This result is consistent with previous findings showing that RGS7 is expressed in melanoma, and is also indicated in multiple datasets in BioGPS, in cbioportal (Supplementary Table ) as well as an additional 29 melanoma samples used in this study (Supplementary Fig. ). To validate the extent to which RGS7 is expressed in human melanomas […]


De novo mutations implicate novel genes in systemic lupus erythematosus

Hum Mol Genet
PMCID: 5886157
PMID: 29177435
DOI: 10.1093/hmg/ddx407

[…] DNMT3A, PRKCD, MICALL1, LRP1, and PNPLA1—have CADD Phred scores >30, placing them in the top 0.1% of possible damaging mutations in the human genome (). We further explored the function, expression (BioGPS), existing autoimmunity associations (ImmunoBase), and gene-level constraint against missense mutations (ExAC), of the DNM genes to build a profile of a priori evidence of a role in SLE pathoge […]


DGIdb 3.0: a redesign and expansion of the drug–gene interaction database

Nucleic Acids Res
PMCID: 5888642
PMID: 29156001
DOI: 10.1093/nar/gkx1143

[…] ional tools, bringing the total number of known platforms that utilize the DGIdb to 10. These platforms are GeneCards (, CVE (), rDGIdb (), PANDA (), iCAGES (, BioGPS (), Omics Pipe (), GEMINI (), StationX ( and IHLDB.rf ( These integrations highlight the accessibility and utility of the DGIdb API, which has be […]


Genome wide profiling of nardilysin target genes reveals its role in epigenetic regulation and cell cycle progression

Sci Rep
PMCID: 5665917
PMID: 29093577
DOI: 10.1038/s41598-017-14942-4

[…] y, and JUNB, a binding partner of the AP-1 family, have been reported to be involved in a wide range of biological processes including cell growth, differentiation, and apoptosis,. Gene annotation by BioGPS indicated that Nrdc is ubiquitously expressed in mammalian tissues, while ELK4 and JUNB are highly enriched in mast cells and macrophages, respectively, suggesting the overlapped expression of […]


Long noncoding RNA SFTA1P promoted apoptosis and increased cisplatin chemosensitivity via regulating the hnRNP U GADD45A axis in lung squamous cell carcinoma

PMCID: 5722577
PMID: 29228625
DOI: 10.18632/oncotarget.22138

[…] n both cell lines (Figure ). And this result was further verified by cytoplasmic and nuclear RNA fractionation analysis (Figure ). More importantly, according to RNA-Seq gene expression profiles from BioGPS Database [], we found that lncRNA SFTA1P was specifically highly expressed in the lung (Figure ). […]


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BioGPS institution(s)
Department of Molecular and Experimental Medicine, The Scripps Research Institute, La Jolla, CA, USA
BioGPS funding source(s)
National Institutes of Health [GM089820, GM083924, TR001114]

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