BioGPS

[…] Human JMJD1B is highly expressed in hematopoietic cells, retinal tissue, and pineal glands (http://biogps.org), suggesting that it plays a role in development and/or maintenance of proper cellular functions in these cells. Similar to human hematopoietic cells, mouse HSPCs also expressed elevated JM […]

[…] tary Fig. , both cell types express RGS7 to various degrees. This result is consistent with previous findings showing that RGS7 is expressed in melanoma, and is also indicated in multiple datasets in BioGPS, in cbioportal (Supplementary Table ) as well as an additional 29 melanoma samples used in this study (Supplementary Fig. ). To validate the extent to which RGS7 is expressed in human melanomas […]

[…] DNMT3A, PRKCD, MICALL1, LRP1, and PNPLA1—have CADD Phred scores >30, placing them in the top 0.1% of possible damaging mutations in the human genome (). We further explored the function, expression (BioGPS), existing autoimmunity associations (ImmunoBase), and gene-level constraint against missense mutations (ExAC), of the DNM genes to build a profile of a priori evidence of a role in SLE pathoge […]

[…] ional tools, bringing the total number of known platforms that utilize the DGIdb to 10. These platforms are GeneCards (http://www.genecards.org), CVE (), rDGIdb (), PANDA (), iCAGES (icages.usc.edu), BioGPS (), Omics Pipe (), GEMINI (), StationX (www.stationxinc.com) and IHLDB.rf (www.lungcancerdatabase.com). These integrations highlight the accessibility and utility of the DGIdb API, which has be […]

[…] y, and JUNB, a binding partner of the AP-1 family, have been reported to be involved in a wide range of biological processes including cell growth, differentiation, and apoptosis,. Gene annotation by BioGPS indicated that Nrdc is ubiquitously expressed in mammalian tissues, while ELK4 and JUNB are highly enriched in mast cells and macrophages, respectively, suggesting the overlapped expression of […]

[…] n both cell lines (Figure ). And this result was further verified by cytoplasmic and nuclear RNA fractionation analysis (Figure ). More importantly, according to RNA-Seq gene expression profiles from BioGPS Database [], we found that lncRNA SFTA1P was specifically highly expressed in the lung (Figure ). […]