BioGRID statistics

info info

Citations per year

Number of citations per year for the bioinformatics software tool BioGRID

Tool usage distribution map

info info

Associated diseases

This word cloud represents BioGRID usage per disease context

Popular tool citations

chevron_left Protein-protein interaction databases chevron_right
Want to access the full stats & trends on this tool?


BioGRID specifications


Unique identifier OMICS_01901
Name BioGRID
Alternative names Biological General Repository for Interaction Datasets, The bio grid
Restrictions to use None
Community driven No
Data access File download, Browse
User data submission Allowed
Version 3.1.156
Maintained Yes


  • Primates
    • Homo sapiens



  • person_outline Mike Tyers
  • person_outline Mark van de Wiel

Additional information

Publications for Biological General Repository for Interaction Datasets

BioGRID citations


Functional signaling and gene regulatory networks between the oocyte and the surrounding cumulus cells

BMC Genomics
PMCID: 5946446
PMID: 29747587
DOI: 10.1186/s12864-018-4738-2

[…] First, we produced a comprehensive PPI database. We downloaded the databases from BioGRID [], MINT [], DIP [] and IntAct [] and filtered them to retain the interactions from cow, human, mouse, pig, rabbit and rat. The gene or protein identifiers were then converted to Ensemble gene […]


Network inference reveals novel connections in pathways regulating growth and defense in the yeast salt response

PLoS Comput Biol
PMCID: 5940180
PMID: 29738528
DOI: 10.1371/journal.pcbi.1006088

[…] idence interactions were included, we required that interactions from high-throughput datasets were identified by at least two, separate experimental methods. PPIs were predominantly sourced from the BioGRID database [] and included non-directed, PPI interactions and directed, post-translational modifications, including phosphorylation. To maximize inclusion of signaling pathways, the background n […]


LncRNA OIP5 AS1 is overexpressed in undifferentiated oral tumors and integrated analysis identifies as a downstream effector of stemness associated transcription factors

Sci Rep
PMCID: 5935738
PMID: 29728583
DOI: 10.1038/s41598-018-25451-3

[…] c stem cells and cancer cell lines were accessed through ENCODE, Roadmap and ChIPBase v2 database and UCSC genome browser was used to visualize the gene location and transcript graphic maps. RAIN and BioGRID v3.4 databases were used to screen lncRNAs-RNA/Protein interaction network and validated data of protein-protein interaction respectively,. Cytoscape v3 was used for visualizing molecular inte […]


Validation of systems biology derived molecular markers of renal donor organ status associated with long term allograft function

Sci Rep
PMCID: 5934379
PMID: 29725116
DOI: 10.1038/s41598-018-25163-8

[…] nal function. Next, all molecular features of donor organ status affecting outcome identified above were mapped on a hybrid interaction network including protein-protein interaction data from IntAct, BioGrid, and Reactome together with computationally inferred relations. The organ status-transplant outcome specific molecular interaction subgraph was extracted from the network discarding molecular […]


Determining the minimum number of protein protein interactions required to support known protein complexes

PLoS One
PMCID: 5919440
PMID: 29698482
DOI: 10.1371/journal.pone.0195545

[…] n complex datasets, CYC2008 [], MIPS [], and Aloy et al.’s set [, ] without any known PPIs, to estimate the minimum number of PPIs, and to pairs of CYC2008 and eight PPI datasets (STRING [], MINT [], BioGRID [], DIP [], BIND [], WI-PHI [], IntAct [, ], and iRefIndex []) to estimate the minimum number of additional PPIs.However, as mentioned above, known PPI data suffers from a significant amount o […]


New perspectives: systems medicine in cardiovascular disease

BMC Syst Biol
PMCID: 5921396
PMID: 29699591
DOI: 10.1186/s12918-018-0579-5
call_split See protocol

[…] d Genomes (KEGG) [], and WikiPathways [] as well as disease-specific databases such as the Online Mendelian Inheritance in Man (OMIM) resource []. Databases focusing on molecular interactions include BioGRID [], IntAct [] and STRING []. Further knowledge sources include drug-target databases, which connect therapeutica and targeted proteins and disease-target databases, which contain diseases know […]

Want to access the full list of citations?
BioGRID institution(s)
Institute for Research in Immunology and Cancer, Universite de Montréal, Montréal, QC, Canada; The Lunenfeld-Tanenbaum Research Institute, Mount Sinai Hospital, Toronto, ON, Canada; Lewis-Sigler Institute for Integrative Genomics, Princeton University, Princeton, NJ, USA; School of Biological Sciences, University of Edinburgh, Edinburgh, UK; Centre Hospitalier de l’Universite Laval (CHUL), Quebec, QC, Canada
BioGRID funding source(s)
Supported by National Institutes of Health [R01OD010929 and R24OD011194]; Biotechnology and Biological Sciences Research Council [BB/F010486/1]; National Institutes of Health National Heart, Lung and Blood Institute [U54HL117798 Curation Core, Garret FitzGerald overall]; Genome Canada Largescale Applied Proteomics; Ontario Genomics Institute (OGI-069); Genome Quebec International Recruitment Award and a Canada Research Chair in Systems and Synthetic Biology.

BioGRID reviews

star_border star_border star_border star_border star_border
star star star star star

Be the first to review BioGRID