A biological library of random peptides can be constructed, displayed and screened, using phage display and other surface display technologies. The target is generally defined as the substance used to screen the library, and the cognate partner of the target is referred to as the template. The screening of the library with an intended target is termed biopanning or panning for short.
Compiles experimental data dealing with antibody and T-cell epitopes studied in various animal species encompassing humans and non-human primates. IEDB proposes a repository allowing six types of searches, including queries by assay, host or epitope, coupled to utilities for t- or b-cell epitope prediction. Data available on this database is derived from various diseases such as allergic or infectious ones as well as from diseases associated with transplantation.
Provides a database of peptide sequences. PepBank is an online resource with biological and medical applications allowing: (i) the prediction of binding partners of biologically interesting peptides, (ii) the development of peptide-based therapeutic or diagnostic agents, or (iii) the forecasting of molecular targets or binding specificities of peptides resulting from phage display selection. The source of peptide sequence data comes from text mining of MEDLINE abstracts. It also includes peptide sequence data from public sources (ASPD and UniProt).
Provides access to biopanning results of random peptide libraries. BDB is an update of MimoDB 2.0 and follows its data collection methods, data inclusion criteria and core data organization. The database contains more than 2000 sets of biopanning data collected from published papers, including peptide sequences, targets, known templates, peptide libraries and crystal structures of target-template or target-peptide complexes. A series of tools is also available.