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BIOPEP specifications


Unique identifier OMICS_06362
Interface Web user interface
Restrictions to use None
Computer skills Basic
Stability Stable
Maintained Yes


  • person_outline Anna Iwaniak <>
  • person_outline Piotr Minkiewicz <>
  • person_outline Malgorzata Darewicz <>

Publication for BIOPEP

BIOPEP citations


Stability of Antiradical Activity of Protein Extracts and Hydrolysates from Dry Cured Pork Loins with Probiotic Strains of LAB

PMCID: 5946306
PMID: 29690547
DOI: 10.3390/nu10040521

[…] of hydrolysates after in vitro digestion and simulated absorption, were analyzed using the in silico approach. the potential of biological activity was evaluated using tools available in the biopep database i.e., “profiles of potential biological activity” for distinguishing all peptides with antioxidant properties and “calculations” to determine the frequency of bioactive fragment […]


Large scale mapping of bioactive peptides in structural and sequence space

PMCID: 5774755
PMID: 29351315
DOI: 10.1371/journal.pone.0191063

[…] and they do not evolve under independent evolutionary constraints. in this work we performed a large-scale mapping of bps in sequence and structural space. using well curated bp deposited in biopep database, we searched for exact matches in non-redundant sequences databases. proteins containing bps, were used in fold-recognition methods to predict the corresponding folds and bps […]


Predicted Release and Analysis of Novel ACE I, Renin, and DPP IV Inhibitory Peptides from Common Oat (Avena sativa) Protein Hydrolysates Using in Silico Analysis

PMCID: 5742776
PMID: 29207547
DOI: 10.3390/foods6120108

[…] with protein sequences obtained from the uniprot database, available at (). each protein sequence was digested in silico with papain (ec or ficin (ec using biopep, which is available at [], and the method shown in ., the peptides that resulted from oat protein hydrolysates were ranked for bioactivity […]


Characterization and Identification of Cryptic Biopeptides in Carya illinoinensis (Wangenh K. Koch) Storage Proteins

PMCID: 5723967
PMID: 29279842
DOI: 10.1155/2017/1549156

[…] nut protein sequences were obtained from the genbank data ( [] and analyzed to obtain the profile of cryptic peptides with putative functional activity using the biopep database ( []. nut protein sequences for analysis in silico are as follows: glutelin (44aa, superfamily glutelin, genbank accession: aac69515.1), 11s legumin […]


Development of Novel Promiscuous Anti Chemokine Peptibodies for Treating Autoimmunity and Inflammation

PMCID: 5703867
PMID: 29218043
DOI: 10.3389/fimmu.2017.01432

[…] to yield two bands corresponding to 5,123 and 868 bp. the positive colonies were verified by dna sequencing., the constructs were transfected into hek-293t cells using fugene 6 (roche). each biopep construct was transfected into two wells of a 6-well plate. one well was dedicated for western blot (wb) analysis, and the second well was dedicated for the establishment of a stable pool. […]


Antihypertensive properties of tilapia (Oreochromis spp.) frame and skin enzymatic protein hydrolysates

PMCID: 5678373
PMID: 29151830
DOI: 10.1080/16546628.2017.1391666

[…] from tilapia frame and skin can potentially be precursors of antihypertensive peptides according to the result of biopep analyses. the aim was to generate peptides with inhibitory effects against angiotensin-converting enzyme (ace) and renin from tilapia frame and skin protein isolates (fpi and spi). […]

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BIOPEP institution(s)
University of Warmia and Mazury in Olsztyn, Chair of Food Biochemistry, Olsztyn-Kortowo, Poland

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