Assists researchers in obtaining comprehensive biosynthesis target molecules based on the BKM-React reactions. Biosynther is a web-based tool that implements user-customized pathway search engines by removing some nodes and/or edges to find the biosynthesis pathways. It allows researchers to interactively explore, step by step, the biosynthetic potentials of precursor chemicals. The software can be useful in metabolic engineering.
Key Laboratory of Combinatorial Biosynthesis and Drug Discovery (Wuhan University), Ministry of Education, and Wuhan University School of Pharmaceutical Sciences, Wuhan, China; State Key Laboratory of Software Engineering (Wuhan University) and Wuhan University School of Computer Sciences, Wuhan, China; Key Laboratory of Systems Microbial Biotechnology, Tianjin Institute of Industrial Biotechnology, Chinese Academy of Sciences, Tianjin, China
Biosynther funding source(s)
Supported by the National Science Foundation of China [31270101; 31570092]; and the national high technology research and development program [2012CB721000; 2012AA023402].