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BIPS specifications


Unique identifier OMICS_07471
Alternative name Biologic Interactions and Network Analysis Interolog Prediction Server
Interface Web user interface
Restrictions to use None
Computer skills Basic
Stability Stable
Maintained Yes

Publication for Biologic Interactions and Network Analysis Interolog Prediction Server

BIPS citations


In Silico Designing and Analysis of Inhibitors against Target Protein Identified through Host Pathogen Protein Interactions in Malaria

PMCID: 4739458
PMID: 27057354
DOI: 10.1155/2016/2741038

[…] nteraction data fetched from protein interaction database STRING, and computationally predicted interactions.The computational prediction of host-pathogen protein interactions was carried out through BIPS, that is, BIANA interolog prediction server ( []. The whole proteome of Plasmodium falciparum, downloaded from UniProt (http://www.uniprot.o […]


PPCM: Combing Multiple Classifiers to Improve Protein Protein Interaction Prediction

Int J Genomics
PMCID: 4619929
PMID: 26539460
DOI: 10.1155/2015/608042

[…] d, structure-based, network topology-based, and sequence-based features []. Each individual computational PPI prediction method utilizes only one or few input sources for PPI prediction. For example, BIPS only takes protein sequences as input for Interolog searching []. Bio::Homology::InterologWalk takes protein sequences and well-known PPI networks as input []. Although these methods using single […]


Prediction of host pathogen protein interactions between Mycobacterium tuberculosis and Homo sapiens using sequence motifs

BMC Bioinformatics
PMCID: 4456996
PMID: 25887594
DOI: 10.1186/s12859-015-0535-y

[…] BLAST (Basic local alignment search tool) [] was employed to compute sequence similarities. Query protein sequences were aligned against all sequences with known interactions stored in the databases BIPS [] and HPIDB []. BIPS and HPIDB are integrated databases including several data sources such as DIP [] and IntAct [], and both of the databases allow the users to set the parameters freely. The e […]


Complementing the Eukaryotic Protein Interactome

PLoS One
PMCID: 3688968
PMID: 23825550
DOI: 10.1371/journal.pone.0066635

[…] score value is experimentally chosen to yield roughly the same number of transferred interactions as STRING(2).In the entire InteroPORC prediction set 17,111 physical interactions and in the selected BIPS:BIANA set 7,073 interactions are included. With 28,155 links between proteins the interaction set from the STRING(1) is the largest, the STRING(2) set is only slightly larger (15,795 interactions […]


Protein Protein Interactions: Gene Acronym Redundancies and Current Limitations Precluding Automated Data Integration

PMCID: 5314489
PMID: 28250396
DOI: 10.3390/proteomes1010003
call_split See protocol

[…] Protein networks and list of interacting proteins were carried out using PSICQUIC [], DASMI [] and BIPS []. These three search engines are representative examples of popular web-based tools frequently used by researchers in the field and able to merge protein interaction data combining the informat […]


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BIPS institution(s)
Structural Bioinformatics Laboratory (GRIB-IMIM), Universitat Pompeu Fabra, Barcelona Research Park of Biomedicine (PRBB), Barcelona, Catalonia, Spain

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