- Unique identifier:
- Graphical user interface
- Operating system:
- Unix/Linux, Mac OS, Windows
- Registration required:
- Software type:
- Restrictions to use:
- License purchase required
- Computer skills:
- Documentation: https://www.blast2go.com/images/b2g_pdfs/b2g_user_manual.pdf
(Conesa et al., 2005)
Blast2GO: a universal tool for annotation, visualization and analysis in functional genomics research.
PMID: 16081474 DOI: 10.1093/bioinformatics/bti610
(Conesa and Götz, 2008)
Blast2GO: A comprehensive suite for functional analysis in plant genomics.
Int J Plant Genomics.
PMID: 18483572 DOI: 10.1155/2008/619832
(Götz et al., 2008)
High-throughput functional annotation and data mining with the Blast2GO suite.
Nucleic Acids Res.
PMID: 18445632 DOI: 10.1093/nar/gkn176
(Aparicio et al., 2006)
Blast2GO goes grid: developing a grid-enabled prototype for functional genomics analysis.
Stud Health Technol Inform.
Bioinformatics Department, Centro de Investigación Príncipe Felipe, Valencia, Spain
Supported by the Spanish Ramon y Cajal Program and the National Institute of Bioinformatics (a platform of Genoma Espana).
3 user reviews
3 user reviews
Overall this program is easy to use, but I have many complaints about how commercial it has become. The free version has become virtually unusable for even relatively small NGS dataset due to speed and lack of very basic functionality (such as selecting sequences by name).
Above all else though, consider this a warning to anyone who wants to use the basic version for their analysis. BLAST2GO BASIC WITHHOLDS YOUR RESULTS AND DOESN'T NOTIFY YOU. I ran enrichment analysis side by side with the PRO and Basic versions of the software with the exact same input dataset and parameters. Enrichment analysis with the basic version gave me no significantly enriched GO categories, while the PRO version gave me many expected enriched GO categories for my dataset. Had I not done the side-by-side analysis I easily could have tried to publish false results showing that there were no significantly enriched GO categories in my dataset, and I never would have known otherwise.
Other functions are grayed out in the basic version, showing that you need to pay to gain access to that tool, while they leave a nonfunctional version of the enrichment test in there. While I generally can get behind entrepreneurship, Blast2GO's push for people to buy their PRO package is dishonest and may have led to the publication of countless false results. Who knows what other Blast2GO Basic functions are secretly withholding results. If anyone else is so inclined, please do your own tests to find out and let others know.
As the makers of Blast2GO we write the first review here: Blast2GO is a professional data analysis tool for functional genomics which offers easy genome wide functional annotation. The free version covers the whole process - the paid PRO version offers additional functions for more ease and faster data processing. Give it a try.