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Citations per year

Number of citations per year for the bioinformatics software tool Blaze

Tool usage distribution map

This map represents all the scientific publications referring to Blaze per scientific context
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Blaze specifications


Unique identifier OMICS_19689
Name Blaze
Alternative name FieldScreen
Software type Application/Script
Interface Graphical user interface
Restrictions to use None
Computer skills Medium
Stability Stable
Maintained Yes


  • person_outline Timothy Cheeseright

Publication for Blaze

Blaze citations


Discovery of Compounds that Positively Modulate the High Affinity Choline Transporter

PMCID: 5326799
PMID: 28289374
DOI: 10.3389/fnmol.2017.00040

[…] The Cresset field based virtual screening tool, Blaze (formerly called FieldScreen), (Cheeseright et al., , ) was utilized to search the full Pfizer compound screening collection to identify compounds similar to literature CHT positive allosteric m […]


Discovery of Small Molecules that Inhibit the Disordered Protein, p27Kip1

Sci Rep
PMCID: 4623604
PMID: 26507530
DOI: 10.1038/srep15686

[…] the model in the next round of screening.The consensus field maps for Group 1 and 2 molecules were used to query a database of 10,455 fragment-like molecules from ChemDiv ( using the FIeldScreen module in Forge. Of the 215 molecules with the highest field similarity scores, 184 compounds were purchased. However, 106 of these were poorly soluble under our assay conditions and not s […]


Three Dimensional Compound Comparison Methods and Their Application in Drug Discovery

PMCID: 5005041
PMID: 26193243
DOI: 10.3390/molecules200712841

[…] D representations: e.g. BCI [], RASCAL [], MOLPRINT2D [], and SIMCOMP [], which use two-dimensional structure fingerprint or graph matching3D representations: e.g. ROCS [], USR [], PL-PatchSurfer [], FieldScreen [] that use 3D features such as volume, atomic distances, surfaces, or fields.Historically, 1D and 2D methods have been widely in part because chemical molecules are typically represented […]


Prospective performance evaluation of selected common virtual screening tools. Case study: Cyclooxygenase (COX) 1 and 2

Eur J Med Chem
PMCID: 4444576
PMID: 25916906
DOI: 10.1016/j.ejmech.2015.04.017

[…] to be performed. Tresadern et al. also included a prospective part in their comparison, where they evaluated the performance of Extended-connectivity fingerprints (ECFP) 6, Ftrees, Topomers, Cresset FieldScreen, and ROCS OpenEye Shape Tanimoto (OEST), OpenEye ComboScore (OECS), and OpenEye electrostatics in identifying ligands for the corticotropin releasing factor 1 receptor. However, the prospe […]


Small Molecule facilitated Degradation of ANO1 Protein

PMCID: 4036244
PMID: 24599954
DOI: 10.1074/jbc.M114.549188
call_split See protocol

[…] Virtual screens and pharmacophore alignments were performed with the Cresset suite of programs, including FieldAlign and FieldScreen (, ). Structure-activity relationship and quantitative structure-activity relationship analysis were performed using Schrödinger's chemoinformatics program, Canvas (Canvas, version 1.5, Sc […]


4D Flexible Atom Pairs: An efficient probabilistic conformational space comparison for ligand based virtual screening

J Cheminform
PMCID: 3156737
PMID: 21733172
DOI: 10.1186/1758-2946-3-23

[…] in comparison to the 4D FAPOA. The optimal assignment kernel (OAK) [,] and its flexibility extension, the OAKFLEX [], were also evaluated in this earlier publication.Cheeseright et al. [] introduced FieldScreen as a multiconformer-based VS tool. FieldScreen utilizes a database that contains conformers of each molecule. Therefore, it operates on a conformational ensemble in a similar way as the 4D […]

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Blaze institution(s)
Cresset BioMolecular Discovery Ltd., BioPark Hertfordshire, Hertfordshire, UK

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