BowTieBuilder specifications


Unique identifier OMICS_17474
Name BowTieBuilder
Interface Web user interface, Application programming interface
Restrictions to use None
Input data A set of source and/or target proteins.
Computer skills Basic
Stability No
Maintained No


This tool is not available anymore.

Additional information

Publication for BowTieBuilder

BowTieBuilder citations


Pathways on demand: automated reconstruction of human signaling networks

NPJ Syst Biol Appl
PMCID: 5516854
PMID: 28725467
DOI: 10.1038/npjsba.2016.2

[…] set of negatives (). For each algorithm, we aggregated the reconstructions of these pathways to measure the precision and recall ( and ). We observed that ANAT, PCSF, RESPONSENET, SHORTESTPATHS, and BOWTIEBUILDER achieved values of recall <0.1. While IPA returned sub-networks with larger recall values, the precision was never above 0.2. RWR achieved the best precision for recall values between 0. […]


Disease Gene Interaction Pathways: A Potential Framework for How Disease Genes Associate by Disease Risk Modules

PLoS One
PMCID: 3167857
PMID: 21915342
DOI: 10.1371/journal.pone.0024495

[…] ation on these diseases in the literature.We demonstrated that complex diseases often have dysfunctions of multiple biological modules or pathways. Similar to traditional approaches (e.g. PathFinder, BowTieBuilder and FASPAD), our method also allows inferring biological pathways in molecular networks when a set of source and/or target proteins are given. As for FASPAD and Pandora, our method is si […]

BowTieBuilder institution(s)
Center for Bioinformatics Tübingen (ZBIT), University of Tübingen, Tübingen, Germany
BowTieBuilder funding source(s)
This work was funded by the German Federal Ministry of Education and Research (BMBF) in the project 'National Genome Research Network' (NGFNplus) under grant number 01GS08134 and 'HepatoSys' under grant number 0313080 L.

BowTieBuilder reviews

star_border star_border star_border star_border star_border
star star star star star

Be the first to review BowTieBuilder