Collects and stores blood–brain barrier (BBB) transport information with positive as well as negative results. Brainpeps allows to prioritize peptide choices for evaluating different BBB responses or studying quantitative structure-property relationships of peptides. Researchers can search the database by peptide nomenclature (e.g. peptide name, letter code), BBB method (e.g. multiple time regression, efflux), BBB response value (e.g. Kin, kout) and literature (author, year, journal).
Drug Quality and Registration Group, Faculty of Pharmaceutical Sciences, Ghent University, Ghent, Belgium; Department of Telecommunications and Information Processing, Faculty of Engineering and Architecture, Ghent University, Belgium; Faculty of Medicine and Health Sciences, Ghent Hospital University, Ghent, Belgium; Department of Radiotherapy and Nuclear Medicine, Faculty of Medicine and Health Sciences, Ghent Hospital University, Ghent, Belgium; Departments of Physiology and Medical Imaging, Faculty of Veterinary Medicine, Ghent University, Belgium; Pennington Biomedical Research Center, BBB Group, Baton Rouge, LA, USA
Brainpeps funding source(s)
This work was supported by a PhD grant of Institute for the Promotion of Innovation through Science and Technology in Flanders (IWT-Vlaanderen).