A browsable repository of personalized cancer DNA breakpoint profiles mapped over the entire genomes of 99 cancer and matched control pairs from five cancer types viz. glioblastoma multiforme (GBM), breast invasive carcinoma (BRC), lung adenocarcinoma (LUAD), ovarian serous cystadenocarcinoma (OV) and head and neck squamous cell carcinoma (HN). We also provide functionality of visualizing and comparing DNA breakpoint profiles between samples of same cancer type or across different cancer types using BreCAN-DB. Users can download breakpoint profiles from the database or may submit their data to be integrated in BreCAN-DB.
School of Computational and Integrative Sciences, Jawaharlal Nehru University, New Delhi, India; GNR Center for Genome Informatics, Institute of Genomics and Integrative Biology, CSIR, Delhi, India; Proteomics and Structural Biology Unit, Institute of Genomics and Integrative Biology, CSIR, Delhi, India
BreCAN-DB funding source(s)
Department of Biotechnology for BINC-SRF; Council of Scientific and Industrial Research for SPM-JRF and CSIR Project BSC0123 (GENCODE-A); Senior Research Fellowship from Wellcome Trust/Department of Biotechnology India Alliance [500127/Z/09/Z]