DNA methylation contributes to the epigenetic regulation of many key developmental processes including genomic imprinting, X-inactivation, genome stability and gene regulation. Bisulfite conversion of genomic DNA combined with next-generation sequencing (BS-seq) is widely used to measure the methylation state of a whole genome, the methylome, at single-base resolution (Lister et al., 2009; Bock et al., 2010; Harris et al., 2010).
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Enables to examine the multi-omics integrated analysis and supplies users a way…
Enables to examine the multi-omics integrated analysis and supplies users a way to study their own multi-omics data. It works on the integrated analysis of gene expression, DNA methylation, and…
Simulates whole-genome inherited bisulphite sequencing data. MethInheritSim…
Simulates whole-genome inherited bisulphite sequencing data. MethInheritSim simulates a multi-generation methylation case versus control experiment with inheritance relation using a real control…
Allows to identify candidate genomic regions for differential…
Allows to identify candidate genomic regions for differential hydroxymethylation as a first step in functional studies. DIRECTION is an in-silico, whole epigenome predictor of DNA methylation and…
A method to map DNA methylation data from bisulfite sequencing approaches to…
A method to map DNA methylation data from bisulfite sequencing approaches to CpG sites measured with the widely used Illumina methylation bead-array platforms. Correlations and median absolute…
A software package to map and determine the methylation state of BS-Seq reads.…
A software package to map and determine the methylation state of BS-Seq reads. Bismark is easy to use, very flexible and is the first published BS-Seq aligner to seamlessly handle single- and…
An open-source software tool capable of analysing whole-genome bisulfite…
An open-source software tool capable of analysing whole-genome bisulfite sequencing data with either a gene-centric or gene-independent focus. GBSA’s output can be easily integrated with other…
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