Bisulfite sequencing data analysis bioinformatics software tools

DNA methylation contributes to the epigenetic regulation of many key developmental processes including genomic imprinting, X-inactivation, genome stability and gene regulation. Bisulfite conversion of genomic DNA combined with next-generation sequencing (BS-seq) is widely used…

BS-seq analysis steps

BS-seq analysis workflow

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BS-seq analysis workflow schema

Bisulfite sequencing data analysis bioinformatics software tools

Most Recent Tools

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BioVLAB-mCpG-SN…
Web

BioVLAB-mCpG-SNP-EXPRESS

Enables to examine the multi-omics integrated analysis and supplies users a way…

Enables to examine the multi-omics integrated analysis and supplies users a way to study their own multi-omics data. It works on the integrated analysis of gene expression, DNA methylation, and…

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methInheritSim
Desktop

methInheritSim

Simulates whole-genome inherited bisulphite sequencing data. MethInheritSim…

Simulates whole-genome inherited bisulphite sequencing data. MethInheritSim simulates a multi-generation methylation case versus control experiment with inheritance relation using a real control…

DIRECTION
Desktop
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epiG
Desktop

epiG

Infers epiallelic haplotypes, annotated with CpG methylation marks and…

Infers epiallelic haplotypes, annotated with CpG methylation marks and polymorphisms, from whole genome bisulphite sequencing data, and nucleosome occupancy from NOMe-seq data. The performance of…

Most Popular Tools

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methyLiftover
Desktop

methyLiftover

A method to map DNA methylation data from bisulfite sequencing approaches to…

A method to map DNA methylation data from bisulfite sequencing approaches to CpG sites measured with the widely used Illumina methylation bead-array platforms. Correlations and median absolute…

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Bismark
Desktop

Bismark

A software package to map and determine the methylation state of BS-Seq reads.…

A software package to map and determine the methylation state of BS-Seq reads. Bismark is easy to use, very flexible and is the first published BS-Seq aligner to seamlessly handle single- and…

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GBSA
Desktop

GBSA Genome Bisulfite Sequencing Analyser

An open-source software tool capable of analysing whole-genome bisulfite…

An open-source software tool capable of analysing whole-genome bisulfite sequencing data with either a gene-centric or gene-independent focus. GBSA’s output can be easily integrated with other…

Curators for BS-seq analysis

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