Bisulfite sequencing data analysis bioinformatics software tools

BS-seq analysis steps

BS-seq analysis workflow

Click the icons of the schema to view tools

BS-seq analysis workflow schema
DNA methylation contributes to the epigenetic regulation of many key developmental processes including genomic imprinting, X-inactivation, genome stability and gene regulation. Bisulfite conversion of genomic DNA combined with next-generation…

Bisulfite sequencing data analysis bioinformatics software tools

Most Recent Tools

G T A T C G C T A
epiG
Desktop

epiG

Infers epiallelic haplotypes, annotated with CpG methylation marks and…

Infers epiallelic haplotypes, annotated with CpG methylation marks and polymorphisms, from whole genome bisulphite sequencing data, and nucleosome occupancy from NOMe-seq data. The performance of…

G T A T C G C T A
MACAU
Desktop

MACAU Mixed model Association for Count data via data Augmentation

Allows to simultaneously account for both the over-dispersed, count-based…

Allows to simultaneously account for both the over-dispersed, count-based nature of bisulfite sequencing data, as well as genetic relatedness among individuals. MACAU is a binomial mixed model and an…

G T A T C G C T A
HMM-Fisher
Desktop

HMM-Fisher

Identifies differentially methylated cytosines and regions. Hidden Markov model…

Identifies differentially methylated cytosines and regions. Hidden Markov model (HMM)-Fisher is efficient and robust in identifying heterogeneous differentially methylated (DM) regions. This method…

G T A T C G C T A
HMM-DM
Desktop

HMM-DM

Detects differentially methylated (DM) regions from bisulfite sequencing (BS)…

Detects differentially methylated (DM) regions from bisulfite sequencing (BS) data generated from different protocols, such as whole-genome bisulfite sequencing (WGBS) and reduced representative BS.…

Most Popular Tools

G T A T C G C T A
methyLiftover
Desktop

methyLiftover

A method to map DNA methylation data from bisulfite sequencing approaches to…

A method to map DNA methylation data from bisulfite sequencing approaches to CpG sites measured with the widely used Illumina methylation bead-array platforms. Correlations and median absolute…

G T A T C G C T A
Bismark
Desktop

Bismark

A software package to map and determine the methylation state of BS-Seq reads.…

A software package to map and determine the methylation state of BS-Seq reads. Bismark is easy to use, very flexible and is the first published BS-Seq aligner to seamlessly handle single- and…

G T A T C G C T A
GBSA
Desktop

GBSA Genome Bisulfite Sequencing Analyser

An open-source software tool capable of analysing whole-genome bisulfite…

An open-source software tool capable of analysing whole-genome bisulfite sequencing data with either a gene-centric or gene-independent focus. GBSA’s output can be easily integrated with other…

Curators for BS-seq analysis

By using OMICtools you acknowledge that you have read and accepted the terms of the end user license agreement.