Bisulfite sequencing data analysis software tools
DNA methylation contributes to the epigenetic regulation of many key developmental processes including genomic imprinting, X-inactivation, genome stability and gene regulation. Bisulfite conversion of genomic DNA combined with next-generation sequencing (BS-seq) is widely used to measure the methylation state of a whole genome, the methylome, at single-base resolution (Lister et al., 2009; Bock et al., 2010; Harris et al., 2010).
Base calling
31 tools
Read quality control
108 tools
Adapter trimming
107 tools
Bisulfite conversion rate estimation
1 tool
Bisulfite primer design
11 tools
Read alignment
45 tools
Quality control
12 tools
Methylation scoring
44 tools
Quantitative score assessment
4 tools
Differentially methylated region detection
45 tools
Methylation annotation
14 tools
SNP detection
7 tools
Allele-specific DNA methylation detection
3 tools
Transcription factor binding prediction
1 tool
Tumor purity deconvolution
2 tools
Interpretation
3 tools
EWAS
20 tools
File merging
33 tools
File format conversion
127 tools
File filtering
44 tools
File indexation
26 tools
File comparison
18 tools
File sorting
19 tools
File intersection
6 tools
File parsing-extraction
45 tools
File sampling
15 tools
File splitting
12 tools
File editing
4 tools
Variant aggregation/summarization
6 tools
