Bisulfite sequencing data analysis bioinformatics software tools

BS-seq analysis steps

BS-seq analysis workflow

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BS-seq analysis workflow schema
DNA methylation contributes to the epigenetic regulation of many key developmental processes including genomic imprinting, X-inactivation, genome stability and gene regulation. Bisulfite conversion of genomic DNA combined with next-generation…

Bisulfite sequencing data analysis bioinformatics software tools

Most Recent Tools

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BS-RNA
Desktop

BS-RNA

An efficient, specialized and highly automated mapping and annotation tool for…

An efficient, specialized and highly automated mapping and annotation tool for RNA bisulfite sequencing data. Focusing on both CG and non-CG methylation, BS-RNA can handle the mapping and annotation…

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ampliMethProfil…
Desktop

ampliMethProfiler

Extracts and analyzes the epihaplotype composition of reads from targeted…

Extracts and analyzes the epihaplotype composition of reads from targeted bisulfite sequencing experiments. ampliMethProfiler is a python-based pipeline for the extraction and statistical…

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Bwa-meth
Desktop

Bwa-meth

Aligns bisulfite-treated sequences and compares it to existing aligners. It…

Aligns bisulfite-treated sequences and compares it to existing aligners. It allows indels, local alignments, and it never writes a temporary-file of the reads to disk, instead streaming the in silico…

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ViewBS
Desktop

ViewBS

Explores and visualizes bisulfite sequencing (BS-seq) data. ViewBS has several…

Explores and visualizes bisulfite sequencing (BS-seq) data. ViewBS has several top level commands which determine the required and optimal arguments. These commands can be divided into two parts:…

Most Popular Tools

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methyLiftover
Desktop

methyLiftover

A method to map DNA methylation data from bisulfite sequencing approaches to…

A method to map DNA methylation data from bisulfite sequencing approaches to CpG sites measured with the widely used Illumina methylation bead-array platforms. Correlations and median absolute…

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Bismark
Desktop

Bismark

A software package to map and determine the methylation state of BS-Seq reads.…

A software package to map and determine the methylation state of BS-Seq reads. Bismark is easy to use, very flexible and is the first published BS-Seq aligner to seamlessly handle single- and…

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GBSA
Desktop

GBSA Genome Bisulfite Sequencing Analyser

An open-source software tool capable of analysing whole-genome bisulfite…

An open-source software tool capable of analysing whole-genome bisulfite sequencing data with either a gene-centric or gene-independent focus. GBSA’s output can be easily integrated with other…

Curators for BS-seq analysis

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