Dataset features

Specifications


Application: ChIP-seq analysis, RNA-seq analysis
Number of samples: 103
Release date: Sep 8 2015
Last update date: Oct 24 2018
Access: Public
Diseases: Leukemia, Neoplasms, Leukemia, Myeloid, Acute, Hematologic Neoplasms
Dataset link Transcriptional plasticity promotes primary and acquired resistance to BET bromodomain inhibition

Experimental Protocol


RNA-Seq of DMSO- or JQ1-treated cancer cell lines; ChIP-seq for H3K36me3 and H3K27me3 in a leukemia cell line treated either with DMSO or JQ1, ChIP-seq for H3K27ac in resistant and sensitive mouse and human leukemia. Functional enhancer mapping (STARR-seq) in K-562 treated either with DMSO or JQ1.

Repositories


GEO

GSE63782

ArrayExpress

E-GEOD-63782

ENA

SRP050440

BioProject

PRJNA269063

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Contact


Philipp Rathert