Dataset features

Specifications


Application: Gene expression microarray analysis
Number of samples: 9
Release date: May 2 2009
Last update date: Oct 29 2018
Access: Public
Diseases: Adrenocortical Carcinoma
Chemicals: Aldosterone, Calcium, Cholesterol Esters, Hydrocortisone, Potassium, Sodium, Steroids
Dataset link Torcetrapib induces aldosterone and cortisol production in an intracellular calcium-dependent mechanism

Experimental Protocol


Experimental Goals: 1. To determine whether or not CETP inhibitors induce activation of RAAS pathway in adrenal derived cells, 2. To determine whether adrenocortical cells show a transcriptional response that can be correlated to BP effects. Experimental Background: Aldosterone production by H295R adrenocortical carcinoma cells in response to the treatments described [dimethyl sulfoxide (vehicle), angiotensin II (a CETP inhibitor), or test compound CP-529414 (a CETP inhibitor)] will be analyzed.

Repositories


GEO

GSE15918

BioProject

PRJNA116921

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Contact


William Loging