Dataset features

Specifications


Application: Gene expression microarray analysis
Number of samples: 30
Release date: Jun 5 2010
Last update date: May 3 2013
Access: Public
Diseases: Brain Ischemia, Heart Arrest
Chemicals: Methylene Blue
Dataset link Effect of methylene blue on the genomic response to reperfusion injury induced by cardiac arrest and cardiopulmonary resuscitation in porcine brain

Experimental Protocol


One group of pigs underwent cardiac arrest (CA) without subsequent cardiopulmonary resuscitation (CPR) and the brain of the animals was removed after 5, 20 or 30 min post CA for genome-wide expression study. Two groups of pigs underwent first CA for 12 min with a subsequent 8 min-long CPR and received either an infusion of saline or an infusion of saline with MB from one minute after the start of CPR until 50 min after return of spontaneous circulation (ROSC). In both latter groups the brains were removed for microarray analysis at the following time points: 30, 60, 180 min.

Repositories


GEO

GSE22165

ArrayExpress

E-GEOD-22165

BioProject

PRJNA127705

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Contact


Cecile Martijn