Dataset features

Specifications


Application: RNA-seq analysis
Number of samples: 29
Release date: Jun 21 2018
Last update date: Nov 30 2018
Access: Public
Diseases: Melanoma, Neoplasms
Dataset link LSD1 ablation stimulates anti-tumor immunity and enables checkpoint blockade

Experimental Protocol


Gene expression profiling of in vitro control and LSD1 KD MCF-7 cells (in biological replicates), as well as ex vivo scramble, LSD1 KO and LSD1/MDA5 DKO B16 tumor cells (in biological triplicates) was analyzed by RNA-seq. Genomic occupancy of LSD1, H3K4me1 and H3K4me2 in in vitro control and LSD1 KD MCF-7 cells, as well as ex vivo scramble and LSD1 KO B16 tumor cells was analyzed by ChIP-seq.

Repositories


GEO

GSE112230

ENA

SRP136272

BioProject

PRJNA445303

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Contact


Wanqiang Sheng