Dataset features

Specifications


Application: RNA-seq analysis
Number of samples: 12
Release date: Aug 16 2018
Last update date: Nov 29 2018
Access: Public
Genes: CLEC10A
Taxon: Homo sapiens
Dataset link Systematic perturbation of retroviral LTRs reveals widespread long-range effects on human gene regulation [RNA-seq]

Experimental Protocol


Identify transcriptional changes of CARGO-CRISPRa/CRISPRi by RNA-seq CRISPR dCas9 fusions to target transposable elements in the genome; 'VPR' and 'KRAB' refer to the name of the dCas9 fusion protein expressed in the given sample. 'Sp' and 'Sa' refer to the gRNA scaffold species for the CRISPR targeting construct, and 'LTR5HS' and 'nontarget' refer to the class of transposable element (or none at all) that the CRISPR targeting construct aims to target.

Repositories


GEO

GSE111332

ENA

SRP133817

BioProject

PRJNA436643

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