|Number of samples:||23|
|Release date:||Feb 27 2018|
|Last update date:||Sep 21 2018|
|Dataset link||Argonaute2 and LaminB modulate gene expression by controlling chromatin topology (neuRNA-seq)|
Nascent RNA-seq (neuRNA-seq) in mock, AGO2, LaminB, and Dcr-2 knockdowns. In addition, AGO2 was depleted using an alternative siRNA designed against its 5'UTR (si5UTRAGO2) and rescue with a wild type version of AGO2 (pwahf_ago2) or catalytic mutant AGO2V966M (pwahf_v966m). Three separate experiments are included here, and each experiment has between 2 and 3 biological replicates as indicated. The supplemental counts table contains raw read counts in genes in each sample, and the supplemental_sample_lookup table describes the experimental design. The "experiment" column of the supplemental_sample_lookup table indicates the experiment from which each sample came from. When performing differential expression analysis with these counts, only samples that came from the same experiment should be compared; in particular note that each experiment has its own set of mock control samples.
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