Dataset features

Specifications


Application: miRNA array analysis
Number of samples: 12
Release date: Aug 18 2016
Last update date: Jul 27 2018
Access: Public
Diseases: Leukemia, Neoplasms
Genes: CD34
Dataset link Expression and exosome incorporation of microRNA by leukemia versus nonmalignant hematopoietic progenitors

Experimental Protocol


This experiment sought to compare the cells and exosomes of CD34+ nonmalignant progenitors to those of malignant myeloid cell lines HL-60 and MOLM-14. Cells were cultured under 1% O2 conditions for 48 hours, after which cells and exosomes were collected, and miRNA was extracted for microarray comparison. Normalization included comparison to the additional MOLM-14 cell and exosome samples grown at 1% O2 in GSE55025 (GSM1328048, GSM1328049, GSM1328044, GSM1328045). The complete_normalized_data.txt contains 16 data columns (12 new samples + 4 re-analyzed data).

Repositories


GEO

GSE85769

BioProject

PRJNA339297

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Contact


Noah Hornick