CancerIn | Ligand-based virtual screening

[…] of protein polymorphism (good or bad), polyphen-2, polymorphism phenotyping v2 (benign, possibly damaging or probably damaging), mutationtaster (polymorphism or disease causing), crc: colorectal cancerin order to predict their biological impact, rna splicing- and protein-dedicated bioinformatics analyses were performed as described under materials and methods. results shown in bold […]

[…] viruses, targeted against different cancer cells, are currently undergoing phase iiii clinical trials. the h101ad strain with the e1b55k gene deletion has been approved for treating head and neck cancerin china (oncorine, shanghai sunway biotech). in a previous study, we established a clinical gene therapy model using a novel recombinant ad strain zd55 with e1b55k deletion and tumour necrosis […]

[…] or impending urinary outflow obstructionpreventive measures for metabolic, cardiovascular, and bone complications should be considered for patients on adt.[] see item 7 for bone health in prostate cancerin general, use of steroidal anti-androgens should be discouragedthe care of patients should be coordinated through or taking place in hospitals with specialized oncology service […]

[…] areas. while in age of over 45 years, the age-specific incidence rate of males was higher than that of females both in urban and rural areas (, ). , it was estimated there were 157,750 died from cancerin 2012. the crude mortality of all cancers in shandong province was 164.47/100,000 (207.42/100,000 in males, 120.23/100,000 in females). the age-standardized mortality rates by chinese […]

[…] bcdin3d was most significant in triple-negative breast cancer (tnbc) patients (p = 0.007)., bcdin3d might serve as an important prognostic factor for tnbc patients., breast cancer is the most common cancerin women, and accountfor approximately 23% of allcancer cases and approximately 14% of cancer deaths[]. it is a heterogeneous disease embracing several different phenotypes [], including […]