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CanDL specifications


Unique identifier OMICS_15498
Name CanDL
Alternative name Cancer Driver Log
Restrictions to use None
Community driven No
Data access File download, Browse
User data submission Allowed
Version 1.1
Maintained Yes


  • Primates
    • Homo sapiens



  • person_outline Sameek Roychowdhury

Publication for Cancer Driver Log

CanDL citations


Metaplastic breast cancer in a patient with neurofibromatosis type 1 and somatic loss of heterozygosity

PMCID: 5880258
PMID: 29449315
DOI: 10.1101/mcs.a002352

[…] entification was checked using databases including ENSEMBL (, dbSNP snp150, Catalogue of Somatic Mutations in Cancer hg19 v. 68 (COSMIC;, and Cancer Driver Log (CanDL; ().To calculate the VAF for each SNV identified in the normal blood sample and/or matched tumor sample, we used a custom R script to count indiv […]


Petri net based 2D design of DNA walker circuits

PMCID: 5856876
PMID: 29576759
DOI: 10.1007/s11047-018-9671-4

[…] ation;Charlie (Heiner et al. )—structural and qualitative analysis.If you want to reproduce one of our examples or try your own ones, please follow these steps.Write with your preferred text editor a CANDL specification. Start from the template provided, and adjustthe definition of constants in the group block according to the literals(In) of your DSD graph, see Definition , and the input values;t […]


Resources for Interpreting Variants in Precision Genomic Oncology Applications

PMCID: 5610688
PMID: 28975082
DOI: 10.3389/fonc.2017.00214

[…] ational and hypothetical therapeutic implications, respectively. A similarly structured scoring system is available for indicating therapeutic implications for variants associated with resistance (). Cancer Driver Log (CanDL), an expert-curated database for potential driver mutations in cancer, employs a similar four-level scoring system based on FDA approval, clinical, pre-clinical, and experimen […]


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CanDL funding source(s)
This work was supported by the American Society of Clinical Oncology Young Investigator Award, a Pelotonia postdoctoral fellowship, American Cancer Society grant MRSG-12-194-01-TBG, Prostate Cancer Foundation grant, NHGRI UM1HG006508-01A1, Fore Cancer Research, and Pelotonia.

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