CanDrA statistics

To access cutting-edge analytics on consensus tools, life science contexts and associated fields, you will need to subscribe to our premium service.

Subscribe
info

Citations per year

Citations chart
info

Popular tool citations

chevron_left Driver mutation prioritization chevron_right
Popular tools chart
info

Tool usage distribution map

Tool usage distribution map
info

Associated diseases

Associated diseases

CanDrA specifications

Information


Unique identifier OMICS_05373
Name CanDrA
Software type Package/Module
Interface Command line interface
Restrictions to use None
Operating system Unix/Linux
Programming languages Perl
License GNU General Public License version 2.0
Computer skills Advanced
Stability Stable
Maintained Yes

Versioning


Add your version

Maintainer


  • person_outline Ken Chen <>

Publication for CanDrA

CanDrA in publications

 (3)
PMCID: 5410329
PMID: 28423598
DOI: 10.18632/oncotarget.15802

[…] nucleotide variants; del, deletion; ins, insertion; dup, duplication; inv, inversion., ausing functional prediction tools gemini, sift and polyphen2., bdriver mutation prediction using transfic and candra identified a single mutation by both methods within atrx gene., cdefined as ‘high’ impact by the gemini sequence ontology., dinspection of genecards and pubmed identified the following genes […]

PMCID: 5226594
PMID: 27391340
DOI: 10.18632/oncotarget.10419

[…] analysis for somatic non-synonymous variants using nine different tools such as: dbnsfp v2.0 (includes sift, polyphen2_hdiv, polyphen2_hvar, lrt, mutation taster, mutation accessor and fathmm) [], candra v1.0 [] and provean v.1.1 []. variants called deleterious in nature by at least one software was taken for further analysis. we confirmed the identity of mutations by manual visualization […]

PMCID: 4232638
PMID: 25348012
DOI: 10.1186/s13059-014-0484-1

[…] [], protein variation effect analyzer (provean) [], functional analysis through hidden markov models (fathmm) [], variant effect scoring tool (vest) [], mutationtaster [], cancer driver annotation (candra) [], and others []. additionally, chasm, fathmm, and candra were developed explicitly to differentiate mutations that are likely to constitute cancer drivers from passengers. in particular, […]


To access a full list of publications, you will need to upgrade to our premium service.

CanDrA institution(s)
Department of Bioinformatics and Computational Biology, The University of Texas MD Anderson Cancer Center, Houston, TX, USA
CanDrA funding source(s)
This work was supported in part by the National Institutes of Health [grant number 1R01CA172652, CA168394, CA083639, CA143883, UL1TR000371 and 1U01CA180964]; the MD Anderson Cancer Center Sheikh Khalifa Ben Zayed Al Nahyan Institute of Personalized Cancer Therapy and the National Cancer Institute Cancer Center Support Grant [P30 CA016672].

CanDrA reviews

star_border star_border star_border star_border star_border
star star star star star

Be the first to review CanDrA