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canEvolve specifications


Unique identifier OMICS_10654
Name canEvolve
Interface Web user interface
Restrictions to use None
Programming languages R
Database management system MySQL
Computer skills Basic
Stability Stable
Maintained Yes


  • Primates
    • Homo sapiens


  • person_outline Cheng Li
  • person_outline Parantu Shah

Publication for canEvolve

canEvolve citations


Spatial competition constrains resistance to targeted cancer therapy

Nat Commun
PMCID: 5722825
PMID: 29222471
DOI: 10.1038/s41467-017-01516-1

[…] le cancer. a.s. was supported by a cooperation grant from the french institute cairo and egyptian science and technology development fund. mh, rn and d.f. were supported by itmo ‘physique cancer’ (canevolve pc201306). thanks to v. georget of mri montpellier imaging facilities for assistance with light microscopy, and f. bernex and n. pirot of the montpellier histology facility (rhem)., d.f. […]


Computational Modeling and Treatment Identification in the Myelodysplastic Syndromes

PMCID: 5670191
PMID: 28913766
DOI: 10.1007/s11899-017-0412-z

[…] cancer clinical trials is perhaps just as important as the clinical trials’ primary objectives. the cancer genome atlas (tcga), gene expression omnibus (geo), cbioportal, the cancer genomics hub, canevolve, and others have collected genomic information from a myriad cancer patients, although the lack of comprehensive clinical annotation and therapy response in most of these datasets […]


TRIM11, a direct target of miR 24 3p, promotes cell proliferation and inhibits apoptosis in colon cancer

PMCID: 5349951
PMID: 27888625
DOI: 10.18632/oncotarget.13550

[…] the percentage of apoptotic cells was determined using facs flow cytometry and associated software (beckman)., kaplan-meier survival curves for trim11 were obtained using the tools at based on the gse17536 data set, probe set 226566_at., this process was carried out as described previously [, ]. briefly, the cells were plated in 12-well plates at the density of 2 × […]


Is ovarian cancer a targetable disease? A systematic review and meta analysis and genomic data investigation

PMCID: 5347729
PMID: 27764790
DOI: 10.18632/oncotarget.12633

[…] using web-available datasets, at the aim to evaluate the expression of major potential biomarkers. in particular we accessed retrievable data from tcga through can-evolve portal ( by fisher test analysis, we recognized high expression of vegfa in eoc. this analysis was validated with mann-whitney test in a free dataset […]


Towards cancer aware life history modelling

PMCID: 4581035
PMID: 26056356
DOI: 10.1098/rstb.2014.0234

[…] comments., this work was supported by grants from the australian research council to h.k., and from the agence nationale de la recherche (evocan anr-13-bsv7-0003-01) and inserm (physique cancer, canevolve pc201306) […]


Databases and Web Tools for Cancer Genomics Study

PMCID: 4411507
PMID: 25707591
DOI: 10.1016/j.gpb.2015.01.005

[…] to its high confidence, nonetheless its data volume is limited., with the rapid development of biological technologies, genome-wide tumor profiling has grown drastically in scale and availability. canevolve fulfills the need for data integration and interpretation. canevolve contains integrated data from 90 studies involving more than 10,000 patients. data analysis can be performed […]

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canEvolve institution(s)
Department of Biostatistics and Computational Biology, Dana-Farber Cancer Institute and Harvard School of Public Health, Boston, MA, USA; Department of Biostatistics and Medical Informatics, Akdeniz University, Antalya, Turkey; Department of Bioinformatics, School of Life Science and Technology, Tongji University, Shanghai, China; State Key Laboratory for Diagnosis and Treatment of Infectious Diseases, The First Affiliated Hospital, School of Medicine, Zhejiang University, Hangzhou, China; Department of Medical Oncology, Dana-Farber Cancer Institute and Harvard Medical School, VA Boston Healthcare System, Boston, MA, USA
canEvolve funding source(s)
Supported by National Institutes of Health (NIH) R01 GM077122, the Claudia Adams Barr Program in Innovative Basic Cancer Research, the Multiple Myeloma Career Development award and National Basic Research [973] Program of China No. 2010CB944904; by NIH RO1-124929, PO1-155258, P50-100007 and PO1-78378 and by the Department of Veterans Affairs Merit Review Awards.

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