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Associated diseases

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CanPredict specifications

Information


Unique identifier OMICS_00142
Name CanPredict
Interface Web user interface
Restrictions to use None
Computer skills Basic
Stability No
Maintained No

Maintainer


This tool is not available anymore.

Publications for CanPredict

CanPredict in publications

 (10)
PMCID: 5239569
PMID: 27191992
DOI: 10.18632/oncotarget.9370

[…] located within functionally-related genes. observed significant differences suggest that the mutation under study may be involved in cancer development., several algorithms like chasm [] and canpredict [] treat the differentiation between driver and passenger somatic missense mutations as a classification problem. the random forest classifier is trained to distinguish between driver […]

PMCID: 4480958
PMID: 26111056
DOI: 10.1186/1471-2164-16-S8-S7

[…] trained on a subset of mutations with defined phenotypic effect. in particular, several methods have been developed for discriminating between passenger and cancer driver mutations [,-]. among them, canpredict [] has been the first algorithm for predicting cancer-causing mutations. the method uses a conservation measures from pfam [] hidden markov models and functional information encoded […]

PMCID: 4466581
PMID: 26073592
DOI: 10.1038/srep10641

[…] a abi prism 3730 dna analyzer (life technologies/applied biosystems, carlsbad ca) and has been fully established for use in testing clinical samples for the presence of cancer-associated mutations., canpredict was used to predict whether a non-synonymous variation would be deleterious to the structure and function of ephb4 using biochemical, evolutionary, and domain-function constraints. […]

PMCID: 4100115
PMID: 24886813
DOI: 10.3390/ijms15069670

[…] [,], automute [,], fish [,], ond-crf [], prosms, protsrf, iptree-stab [], mupro, scide [,], scpred [], mustab [,], popmusic, pmut [,,], snap [], snps and gene ontology (snps&go) [], parepro [], canpredict [], nssnpanalyzer [,,], mutpred [], hansa [,], mutation taster [] and beatmusic []., besides studying the protein stability changes upon mutations, the sequence-based machine learning […]

PMCID: 4000980
PMID: 24817905
DOI: 10.1155/2014/653487

[…] suggests that cancer drivers have characteristics similar to mendelian disease mutations []. based on this information, a computational tool for predicting cancer-associated missense mutations, canpredict, was developed []. though quite powerful, generalized prediction methods such as canpredict may fail to achieve the sensitivity and specificity attainable by prediction models tailored […]


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CanPredict institution(s)
Department of Bioinformatics, Genentech, Inc; South San Francisco, CA, USA

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