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CARA specifications


Unique identifier OMICS_03405
Alternative name Computer Aided Resonance Assignment
Software type Package/Module
Interface Command line interface
Restrictions to use None
Operating system Unix/Linux
Computer skills Advanced
Stability Stable
Maintained Yes


No version available

CARA citations


Molecular mechanism of influenza A NS1 mediated TRIM25 recognition and inhibition

Nat Commun
PMCID: 5940772
PMID: 29739942
DOI: 10.1038/s41467-018-04214-8

[…] ples were measured at concentrations ranging between 0.1 and 0.5 mM in 20 mM Na2HPO4, 150 mM NaCl, 0.5 mM TCEP at pH 6.5. All spectra were processed with NMRPipe and analysed using Sparky, CCPNMR and CARA ( For backbone resonance assignments of the PRYSPRY domain, HNCACB, CBCA(CO)NH and HNCA spectra were recorded. Backbone resonance assignment was obtained to a completion of 95 […]


Co(II) Coordination in Prokaryotic Zinc Finger Domains as Revealed by UV Vis Spectroscopy

PMCID: 5745721
PMID: 29386985
DOI: 10.1155/2017/1527247

[…] ). 1H and 15N chemical shifts were calibrated indirectly by using TMS as external references. All NMR spectroscopy data were processed with the TopSpin 3.5 software (Bruker) and analyzed by using the computer-aided resonance assignment [] (CARA) software (downloaded from […]


The Sam Sam interaction between Ship2 and the EphA2 receptor: design and analysis of peptide inhibitors

Sci Rep
PMCID: 5727260
PMID: 29234063
DOI: 10.1038/s41598-017-17684-5
call_split See protocol

[…] Trimethylsilyl-3-propionic acid sodium salt-D4, 99% D, Armar Scientific, Switzerland) (0.0 ppm).Spectra were processed with VNMRJ 1.1D (Varian, Italy) and analyzed with the software NEASY included in CARA ( procedure suggested by Kjaergaard and collaborators was used to estimate chemical shift deviations from random coil values for Hα protons (CSD) ( […]


Structural Basis for EarP Mediated Arginine Glycosylation of Translation Elongation Factor EF P

PMCID: 5615199
PMID: 28951478
DOI: 10.1128/mBio.01412-17

[…] from two-dimensional (2D) 1H-15N HSQC and three-dimensional (3D) HNCA, CBCACONH, and HNCACB backbone experiments, using a constant time during 13C evolution (). The assignment process was assisted by CARA ( and CcpNmr Analysis (63), and 98% of the backbone resonances could be assigned. Missing assignments for residues other than prolines are S123, R133, N140, V164, D175, and G18 […]


Structural Analysis of Porcine Reproductive and Respiratory Syndrome Virus Non structural Protein 7α (NSP7α) and Identification of Its Interaction with NSP9

Front Microbiol
PMCID: 5425468
PMID: 28553277
DOI: 10.3389/fmicb.2017.00853

[…] MRB under BMRB accession number 30014 (). All the NMR experiments were carried out at 298K on a Bruker Avance 600 MHz spectrometer. All spectra were processed using NMRPipe/Draw () and analyzed using CARA ().The structure of NSP7α was refined by CNS () based on the chemical shift assignments and NOE distance restraints. Backbone φ and ψ dihedral angle restraints obtained using TALOS+ (). H-bond re […]


Effect of position specific single point mutations and biophysical characterization of amyloidogenic peptide fragments identified from lattice corneal dystrophy patients

PMCID: 5632800
PMID: 28381645
DOI: 10.1042/BCJ20170125

[…] all 13C and 15N experiments, chemical shifts were calibrated from the gyromagnetic ratio based on the H2O signal. The data were processed using TopSpin 2.0 ( and analyzed using CARA ( […]

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