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Protein carbonylations are widely recognized as the biomarkers for oxidative stress, protein damage, aging/senescence, age-related diseases, and numerous degenerative/other diseases including cancer. While all bio-molecules are prone to oxidative damage, proteins are particularly vulnerable and critical targets because most of the cellular functional-biomass is proteins. A database that provides easy access to information on experimentally-confirmed carbonylated proteins/sites would therefore be a very valuable resource.
(Rao et al., 2018) CarbonylDB: A curated data-resource of protein carbonylation sites. Bioinformatics.