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|Alternative name||Community And Systems-level INteractive Optimization|
Publication for Community And Systems-level INteractive Optimization
Perspectives on Systems Modeling of Human Peripheral Blood Mononuclear Cells
[…] al., ). Furthermore, GEMs derived from human gut microbiome were used to decipher microbe-microbe, diet-microbe and microbe-host interactions. Another GEM based comprehensive computational platform, CASINO (Community And Systems-level INteractive Optimization) was designed to study the effect of diet on microbial communities (Shoaie et al., ). […]
The Human Mucosal Mycobiome and Fungal Community Interactions
[…] between them to the overall simplified community metabolism and elucidate the interactions between the bacteria [,]. Through the generation of comprehensive toolboxes for community modeling, such as CASINO (Community And Systems-level INteractive Optimization), and the use of GEMs for predominant bacteria in human gut, the alteration in the amino acid profile of both feces and serum in response t […]
Elucidation of complexity and prediction of interactions in microbial communities
[…] nities to predict time‐varying interactions between species and their effects on microbial composition. This approach is referred to as dynamic multispecies metabolic modelling (Zhuang et al., ). The CASINO toolbox (Community And Systems‐level INteractive Optimization) was created as a comprehensive platform to analyse gut microbial communities (Shoaie et al., ). The authors used experimental data […]
More than just a gut feeling: constraint based genome scale metabolic models for predicting functions of human intestinal microbes
[…] esses. By combining previous approaches of modeling interspecies interactions and considering the whole microbiota as one entity, a predictive tool for dietary interventions was created . The tool, CASINO—Community And Systems-level Interactive and Optimization—predicts dietary interventions based on interactions between the host, the microbiota, and the applied diet. CASINO was used to model th […]
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