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CASP specifications


Unique identifier OMICS_22395
Alternative names Critical Assessment of Structure Prediction, CASP1, CASP2, CASP3, CASP4, CASP5, CASP6, CASP7, CASP8, CASP9, CASP10, CASP11
Restrictions to use None
Community driven Yes
Data access File download, Browse
User data submission Not allowed
Version 12
Maintained Yes


  • person_outline Ceslovas Venclovas

Publication for Critical Assessment of Structure Prediction

CASP citations


SIRT1 activation with neuroheal is neuroprotective but SIRT2 inhibition with AK7 is detrimental for disconnected motoneurons

PMCID: 5945655
PMID: 29748539
DOI: 10.1038/s41419-018-0553-6

[…] Bank, Iowa City, IA, USA), mouse anti-anti-SMI-32 (1:1000; Biolegend), rabbit anti-p65 (1:1000, Cell Signaling, Danver, MA, USA), rat-anti-CD86 (1:200; BD Biosciences, San Jose, CA, USA), rabbit anti-Casp3.Act (1:200; Cell Signaling), and rabbit anti-AIF1 (1:200; Antibodies-Online, Atlanta, GA, USA). After several washes with 0.1% Tween-20 in TBS solution, the sections were incubated for 2 h with […]


hTERT gene knockdown enhances response to radio and chemotherapy in head and neck cancer cell lines through a DNA damage pathway modification

Sci Rep
PMCID: 5899166
PMID: 29654294
DOI: 10.1038/s41598-018-24503-y

[…] th PBS, cells were incubated with 1:10,000 DAPI/H2O (Sigma-Aldrich, MI, USA) and were observed under fluorescence microscope (Leica, Germany) at room temperature. Primary antibodies were: 1:1000 anti-CASP3 rabbit polyclonal antibody (Abcam, UK), 1:750 anti-BECN1 mouse monoclonal antibody (Abcam, UK), and 1:500 anti-hTERT mouse monoclonal antibody (Abcam, UK). Secondary antibodies were: Alexa Fluor […]


Dual responsive dithio polydopamine coated porous CeO2 nanorods for targeted and synergistic drug delivery

PMCID: 5905827
PMID: 29695903
DOI: 10.2147/IJN.S152002

[…] ide membranes (Millipore, Bedford, MA, USA). The membranes were blocked with 5% nonfat dry milk in TBS containing 0.1% Tween for 1 h at room temperature and then blotted with primary antibodies: anti-Casp9 (1:100), anti-Actin (1:1,000) overnight. After washing, the membranes were incubated with a secondary horseradish peroxidase (HRP)-coupled antibody and visualized using Immobilon HRP substrate ( […]


Opportunities and obstacles for deep learning in biology and medicine

PMCID: 5938574
PMID: 29618526
DOI: 10.1098/rsif.2017.0387

[…] ny sequence homologues. It employs a network architecture formed by one one-dimensional residual neural network and one 2D residual neural network. Blindly tested in the latest CASP competition (i.e. CASP12 []), RaptorX-Contact ranked first in F1 score on free-modelling targets as well as the whole set of targets. In CAMEO (which can be interpreted as a fully automated CASP) [], its predicted cont […]


PVP SVM: Sequence Based Prediction of Phage Virion Proteins Using a Support Vector Machine

Front Microbiol
PMCID: 5864850
PMID: 29616000
DOI: 10.3389/fmicb.2018.00476

[…] al., ). Previously, Manavalan and Lee applied a systematic feature selection protocol and developed a novel quality assessment method called SVMQA (Manavalan and Lee, ), which was the best method in CASP12 blind prediction experiments (Elofsson et al., ; Kryshtafovych et al., ). We applied a similar protocol in our recent studies, including cell-penetrating peptide and DNase I hypersensitivity pr […]


Antiepileptogenic Effect of Subchronic Palmitoylethanolamide Treatment in a Mouse Model of Acute Epilepsy

PMCID: 5861196
PMID: 29593494
DOI: 10.3389/fnmol.2018.00067
call_split See protocol

[…] tion of PEA’s assumed neuroprotective properties we performed neurodegenerative FJC and silver staining, and additionally, immunohistochemical double staining of neuronal nuclei (NeuN) and caspase-3 (CASP3) activation in brain sections of previously perfused brains. FJC staining was conducted following previously reported protocol (Schmued et al., ). Briefly, 40 μm coronal brain sections were coll […]


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CASP institution(s)
Institute of Biotechnology, Graiciuno 8, Vilnius, Lithuania

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