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CAT specifications


Unique identifier OMICS_01676
Name CAT
Alternative name CAZymes Analysis Toolkit
Restrictions to use None
Community driven No
Data access Browse
User data submission Not allowed
Maintained No


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Publication for CAZymes Analysis Toolkit

CAT citations


Uncovering the molecular mechanisms of lignocellulose digestion in shipworms

Biotechnol Biofuels
PMCID: 5840672
PMID: 29527236
DOI: 10.1186/s13068-018-1058-3

[…] hm [] to search against non-redundant (nr) peptide database downloaded from the National Center for Biotechnology Information ( CAZy annotation was carried out using the CAZYmes Analysis Toolkit (CAT) on the BioEnergy Science Center website ( Sequences annotated as glycosyltransferases (GTs) and carboxyl esterases, mostly in […]


An ancient family of lytic polysaccharide monooxygenases with roles in arthropod development and biomass digestion

Nat Commun
PMCID: 5823890
PMID: 29472725
DOI: 10.1038/s41467-018-03142-x
call_split See protocol

[…] e of the sum of all emPAI values in the sample. Proteins identified in the proteomics analysis were annotated via Blastx versus non-redundant NCBI databases. CAZy annotation was carried out using the CAZymes Analysis Toolkit (CAT) on the BioEnergy Science Center website ( and dbCAN ( Putative N-terminal signal peptide cleava […]


Metagenomic Study Suggests That the Gut Microbiota of the Giant Panda (Ailuropoda melanoleuca) May Not Be Specialized for Fiber Fermentation

Front Microbiol
PMCID: 5820910
PMID: 29503636
DOI: 10.3389/fmicb.2018.00229
call_split See protocol

[…] database with parameters “for prokaryotes in representative set” (Moriya et al., ) and other parameters were chosen by default. Carbohydrate-active enzymes annotation was performed using the blast in CAZYmes Analysis Toolkit (CAT) (Park et al., ) ( choosing the sequence based annotation with an E-value cut-off of 10-5 and Bit Score = 60. […]


Whole Genome Sequencing of Fusarium fujikuroi Provides Insight into the Role of Secretory Proteins and Cell Wall Degrading Enzymes in Causing Bakanae Disease of Rice

Front Plant Sci
PMCID: 5711826
PMID: 29230233
DOI: 10.3389/fpls.2017.02013

[…] f against PHIbase: the pathogen–host interaction gene database () was performed to predict potential pathogenicity genes associated with loss of pathogenicity, reduced virulence, lethal, etc. (). The CAZymes Analysis Toolkit (CAT) was used to detect carbohydrate active enzymes (CAZymes) based on the CAZy database (). An annotation method based on association rules between CAZy families and Pfam do […]


Metagenomic Analysis of the Gut Microbiome of the Common Black Slug Arion ater in Search of Novel Lignocellulose Degrading Enzymes

Front Microbiol
PMCID: 5682323
PMID: 29167663
DOI: 10.3389/fmicb.2017.02181
call_split See protocol

[…] EGAN4 software. Further functional assignment was made by searching the predicted proteins against the CAZy database (Lombard et al., ). To do this all predicted sequences were used as a query in the CAZYmes Analysis Toolkit (CAT) (Park et al., ) using the Pfam based annotation tool with an E-value threshold of × 10−4. Further phylogenetic analysis was carried out by subjecting raw sequencing read […]


Metagenomic evidence of stronger effect of stylo (legume) than bahiagrass (grass) on taxonomic and functional profiles of the soil microbial community

Sci Rep
PMCID: 5579253
PMID: 28860520
DOI: 10.1038/s41598-017-10613-6

[…] ein sequences of predicted genes with the KEGG database with an E-value cut-off of 1e−5. Searches for carbohydrate-active enzymes were performed using the CAZy database reference dataset found in the CAZymes Analysis Toolkit web service by protein BLAST with an E-value cut-off of 1e−5. The abundance of predicted genes was estimated using a method analogous to the contig coverage in sequence assemb […]


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CAT institution(s)
Computer Science and Mathematics Division, Oak Ridge National Laboratory, Oak Ridge, TN, USA; Biosciences Division, Oak Ridge National Laboratory, Oak Ridge, TN, USA; Department of Plant Sciences, University of Tennessee, TN, USA
CAT funding source(s)
Supported by the BioEnergy Science Center and by the Genomic Science Program of the Office of Biological and Environmental Research, U.S. Department of Energy.

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