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Provides rapid, accurate and fully automated calculation of tunnels and channels in static structures. The molecules amendable to analysis of CAVER include proteins, nucleic acids or inorganic materials. CAVER can be used either as PyMol plugin or independent application CAVER Analyst. CAVER Analyst has been designed for easy set-up of calculation, visualization of results and efficient data analysis. It can be used for both static structures and molecular ensembles from molecular dynamic simulations or NMR.

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CAVER classification

CAVER specifications

Software type:
Restrictions to use:
Computer skills:
Command line interface, Graphical user interface
Operating system:
Unix/Linux, Mac OS, Windows

CAVER distribution


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CAVER support


  • CAVER <>


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Department of Computer Graphics and Design, Human Computer Interaction Laboratory, Faculty of Informatics, Masaryk University, Brno, Czech Republic; Loschmidt Laboratories, Department of Experimental Biology and Research Centre for Toxic Compounds in the Environment RECETOX, Faculty of Science, Masaryk University, Brno, Czech Republic; Department of Computer Science and Engineering, Faculty of Applied Sciences, University of West Bohemia, Plzen, Czech Republic

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