CAVER specifications


Unique identifier OMICS_04690
Software type Package/Module
Interface Command line interface, Graphical user interface
Restrictions to use None
Operating system Unix/Linux, Mac OS, Windows
Computer skills Advanced
Stability Stable
Maintained Yes


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  • person_outline Jiri Damborsky <>
  • person_outline Barbora Kozlikova <>

CAVER articles

CAVER citations

PMCID: 5310519

[…] to alter the enzyme active site residues to improve or newly establish the binding of a small ligand.77 the zebra web server attempts to systematically identify and analyse adaptive mutations.78 caver and povme2 can be used to analyse tunnel dynamics in trajectories obtained by md simulations.79,80 janus analyses multiple-sequence alignments to predict mutations required for inter-conversion […]

PMCID: 4735121

[…] interactions were set to 10.0 å. the shake algorithm was used for the covalent bonds involving hydrogen [47]. the trajectory of md simulation was analyzed for the structure stability., the program caver 3.0 was used for of access tunnel computation [48]. the x-ray structures were used as input files for caver to find potential access tunnels involved in ligand egress. all the structures […]

CAVER institution(s)
Department of Computer Graphics and Design, Human Computer Interaction Laboratory, Faculty of Informatics, Masaryk University, Brno, Czech Republic; Loschmidt Laboratories, Department of Experimental Biology and Research Centre for Toxic Compounds in the Environment RECETOX, Faculty of Science, Masaryk University, Brno, Czech Republic; Department of Computer Science and Engineering, Faculty of Applied Sciences, University of West Bohemia, Plzen, Czech Republic

CAVER review

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