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CAZy specifications


Unique identifier OMICS_01677
Name CAZy
Alternative name Carbohydrate-Active Enzymes database
Restrictions to use None
Community driven No
Data access Browse
User data submission Not allowed
Maintained Yes




  • person_outline Berrd Henrissat
  • person_outline Dipak Banerjee

Publications for Carbohydrate-Active Enzymes database

CAZy citations


Comparative Genomics Reveals the Core Gene Toolbox for the Fungus Insect Symbiosis

PMCID: 5954228
PMID: 29764946
DOI: 10.1128/mBio.00636-18

[…] pipeline (, employing tools of Augustus (), GeneMark.hmm-ES (), and EVM (). Gene function was inferred from matches to the databases of Pfam (), Merops (), CAZy (), InterProScan (), and Swiss-Prot (). Product descriptions were assigned with homologues with 60% similarity across 60% of the protein length (). CEGMA v2.4.010312 was used to identify the pres […]


A plasmid borne, functionally novel glycoside hydrolase family 30 subfamily 8 endoxylanase from solventogenic Clostridium

PMCID: 5934979
PMID: 29626157
DOI: 10.1042/BCJ20180050
call_split See protocol

[…] gnment figures were generated using the ESPript web server [] available at The studies involved in this work rely on the continued maintenance of the CAZy Database ( [] for analysis and functional correlation of enzyme family members. […]


Highly Promiscuous Oxidases Discovered in the Bovine Rumen Microbiome

Front Microbiol
PMCID: 5945886
PMID: 29780372
DOI: 10.3389/fmicb.2018.00861

[…] cluster (ORFs 2–12) and which are involved in the transport, binding, and degradation of plant cell wall derived oligo- and polysaccharides. The dehydrogenase encoding gene is separated from the last CAZy encoding gene by two other ORFs coding for enzymes that could also participate in the redox process observed in this study, and which present similarities with enzymes from the L-serine biosynthe […]


Comparative systems analysis of the secretome of the opportunistic pathogen Aspergillus fumigatus and other Aspergillus species

Sci Rep
PMCID: 5919931
PMID: 29700415
DOI: 10.1038/s41598-018-25016-4

[…] The predicted secretomes in Aspergillus species were annotated with information on protein family from Pfam database ( and carbohydrate-binding modules from CAZy ( and dbCAN v5.0 ( databases using hmmpress and hmmscan utilities in HMMER3 ( with profile-specific GA (gathering) thresholds […]


The response to selection in Glycoside Hydrolase Family 13 structures: A comparative quantitative genetics approach

PLoS One
PMCID: 5919626
PMID: 29698417
DOI: 10.1371/journal.pone.0196135

[…] lus an arginine residue are conserved in this family across all catalytic members [, ]. The GH13 family has many characterized enzymes with diverse functions which are summarized and clustered in the CAZY database []. GH13 is a highly diverse family in function and is also ubiquitous, being found in all kingdoms of life []. The GH13 family has been subdivided into over 40 subfamilies [, ] by their […]


Comparative Genomics Reveals the Regulatory Complexity of Bifidobacterial Arabinose and Arabino Oligosaccharide Utilization

Front Microbiol
PMCID: 5928203
PMID: 29740413
DOI: 10.3389/fmicb.2018.00776

[…] d via the PaperBLAST tool () and reference databases including SwissProt for characterized protein annotations (), KEGG for reference metabolic pathways (), TCDB for transporter classification () and CAZy for classification of Glycosyde Hydrolases (GHs) (). Orthologs were identified using BLAST-based protein similarity searches and gene neighborhood analysis implemented in SEED. Cellular localizat […]

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CAZy institution(s)
Microbial Physiology, Groningen Biomolecular Sciences and Biotechnology Institute (GBB), University of Groningen, Groningen, Netherlands; Nestle Research Center, Vers-Chez-Les-Blanc, Lausanne, Switzerland
CAZy funding source(s)
Supported by Nestec Ltd and by the University of Groningen and the University of Groningen.

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