Computational protocol: In Silico Prediction and Experimental Confirmation of HA Residues Conferring Enhanced Human Receptor Specificity of H5N1 Influenza A Viruses

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Protocol publication

[…] The structural model of the H5 HA molecule of KAN-1 was constructed using SWISS-MODEL and POLYVIEW-3D and is based on homology modeling using the crystal structure of the H5-HA protein of A/Vietnam/1203/2004 (PDB ID: 2FK0.1) as a template. H5 numbering was based on the mature protein (Gene bank accession: AAS65615.2) and the residues involved in receptor binding were defined according to Duvvuri et al.. […]

Pipeline specifications

Software tools SWISS-MODEL, POLYVIEW-3D
Application Protein structure analysis
Organisms Homo sapiens
Diseases Influenza, Human