Provides a web resource for exploring, visualizing, and analyzing multidimensional cancer genomics data. cBioPortal reduces molecular profiling data from cancer tissues and cell lines into readily understandable genetic, epigenetic, gene expression, and proteomic events. The query interface, combined with customized data storage, enables researchers to interactively explore genetic alterations across samples, genes, and pathways and, when available in the underlying data, to link these to clinical outcomes.
Computational Biology Center, Memorial Sloan-Kettering Cancer Center, New York, NY, USA; Computer Engineering Department, Bilkent University, Ankara, Turkey; Institute of Biomedicine, Department of Medical Biochemistry and Cell Biology, University of Gothenburg, Gothenburg, Sweden; Blueprint Medicines, Cambridge, MA, USA
cBioPortal funding source(s)
Supported by NCI as part of the TCGA Genome Data Analysis Center grant, NCI-U24CA143840, and NCI-R21CA135870, a Stand Up To Cancer Dream Team Translational Research Grant, a Program of the Entertainment Industry Foundation (SU2C-AACR-DT0209), the National Resource for Network Biology (NIH National Center for Research Resources grant numbers P41 RR031228 and GM103504), the NIH NCI R01 CA132744 and the Starr Cancer Consortium (I5-A500).