|Application:||Gene expression microarray analysis|
|Number of samples:||12|
|Genes:||TOX, TOX2, TOX3|
|Taxon:||Homo sapiens, Rattus norvegicus|
|Dataset link||Expression data in HK-2 cells following exposure to CdCl|
Gene expression changes in HK-2 cells were measured following exposure to 9 different compounds over a range of doses and time-points with the aim of finding biological signatures of toxicity. Clustering of the resulting gene expression data revealed 3 groups of nephrotoxic compounds (Tox 1, Tox 2 and Tox 3), each exhibiting their own distinct effect on HK-2 cells. This study measures gene expression changes following exposure to CdCl or control over 12 hrs or 48 hrs. Three biological replicates per compound/time-point.