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CCSB Interactome Database specifications


Unique identifier OMICS_02871
Name CCSB Interactome Database
Restrictions to use None
Maintained Yes


  • Invertebrates
    • Caenorhabditis elegans
  • Plants and Fungi
    • Arabidopsis thaliana
    • Saccharomyces cerevisiae
  • Primates
    • Homo sapiens

Publication for CCSB Interactome Database

CCSB Interactome Database citations


Strength of functional signature correlates with effect size in autism

Genome Med
PMCID: 5501949
PMID: 28687074
DOI: 10.1186/s13073-017-0455-8

[…] mum distance of six jumps roughly as described in Gillis and Pavlidis []. We repeated this for alternative PPI datasets including: I2D [] (v2.9), HPRD [] (release 9), HIPPIE [] (v1.8), IntAct [], the CCSB interactome database [] (HI-III v2.2), STRING [] (v10), and PIPs []. A non-interacting PPI network was created from data from the negatome [] (v2). […]


A visual review of the interactome of LRRK2: Using deep curated molecular interaction data to represent biology

PMCID: 4415485
PMID: 25648416
DOI: 10.1002/pmic.201400390

[…] ieces of evidence present in BioGRID but excluded from further analysis.Finally, we queried other non-IMEx compliant resources including the Human Protein Reference Database (HPRD, ) and CCSB Interactome Database ( ) through their respective websites. HPRD is a centralized platform focused in human data regarding disease association, PTMs, […]


Identifying communities from multiplex biological networks

PMCID: 4690346
PMID: 26713261
DOI: 10.7717/peerj.1525

[…] orks were constructed from different sources of interactions between human genes or proteins. A network of physical binary protein–protein interactions was created from the PSICQUIC portal () and the CCSB Interactome database (), and contains 60,669 direct interactions between 12,110 proteins. A co-expression network was constructed from RNA-Seq data downloaded from the Human Protein Atlas (http:/ […]


Protein interaction networks as metric spaces: a novel perspective on distribution of hubs

BMC Syst Biol
PMCID: 3902029
PMID: 24438364
DOI: 10.1186/1752-0509-8-6

[…] er organisms were downloaded from various databases: the Database of Interacting Proteins ( Version 02/28/2012 [], bioGRID database (, CCSB interactome database (, antAnc database ( Version 2.0, and MINT database ( […]

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CCSB Interactome Database institution(s)
Center for Cancer Systems Biology, Department of Cancer Biology, Dana-Farber Cancer Institute, Boston, MA, USA

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