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CEBS specifications


Unique identifier OMICS_06027
Alternative name Chemical Effects in Biological Systems
Restrictions to use None
Database management system Oracle
Community driven No
Data access File download, Browse
User data submission Allowed
Maintained No


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Publications for Chemical Effects in Biological Systems

CEBS citations


An Integrated Chemical Environment to Support 21st Century Toxicology

Environ Health Perspect
PMCID: 5644972
PMID: 28557712
DOI: 10.1289/EHP1759

[…] n the source data sets is not available in ICE (for example, detailed clinical observations or some study protocol details), but it is available via the provided links and will also be accessible via CEBS () to facilitate integration with other data resources from the NIEHS. […]


Interactive Toxicogenomics: Gene set discovery, clustering and analysis in Toxygates

Sci Rep
PMCID: 5431224
PMID: 28469246
DOI: 10.1038/s41598-017-01500-1

[…] and Affymetrix microarray data of rat liver for 124 liver-active compounds, generated between 2004–2008. The data are available at Strand Life Sciences web page ( and NIH CEBS database ( Although the authors also offer an R package for data and connectivity map-based analysis, this resource is an example of a […]


Assessment of Community Event–Based Surveillance for Ebola Virus Disease, Sierra Leone, 2015

PMCID: 4982166
PMID: 27434608
DOI: 10.3201/eid2208.160205

[…] The CEBS system included community health monitors, community surveillance supervisors, and community health officers, each of whom received job-specific training in the month before beginning operations. […]


Novel Roles for Notch3 and Notch4 Receptors in Gene Expression and Susceptibility to Ozone Induced Lung Inflammation in Mice

Environ Health Perspect
PMCID: 4529014
PMID: 25658374
DOI: 10.1289/ehp.1408852

[…] entially expressed at the Benjamini-Hochberg multiple testing correction adjusted p-value < 0.05. Gene lists were analyzed using Ingenuity Pathway Analysis (QIAGEN). Microarray data were submitted to CEBS (Chemical Effects in Biological Systems; 005-00003-0112-000-3) and GEO (Gene Expression Omnibus; GSE58244).EPIG (extracting microarray gene expression patterns and identifying coexpressed genes) […]


A synthetic library of RNA control modules for predictable tuning of gene expression in yeast

Mol Syst Biol
PMCID: 3094065
PMID: 21364573
DOI: 10.1038/msb.2011.4

[…] cture.html) to determine the predicted secondary structure of the hairpins. No consensus secondary structure was identified from the 41 isolates because of the diversity of associated structures. The CEBs of the recovered hairpins are either completely base paired or contain one or two bulges of different size and location (). To ensure modularity of the synthetic Rnt1p hairpins to other genetic c […]


Protective Role of Interleukin 10 in Ozone Induced Pulmonary Inflammation

Environ Health Perspect
PMCID: 3002191
PMID: 20826374
DOI: 10.1289/ehp.1002182
call_split See protocol

[…] National Center for Biotechnology Information’s Gene Expression Omnibus data repository (, series GSE25095) and the National Institute of Environmental Health Sciences Chemical Effects in Biological Systems database (, accession no. 005-00003-0070-000-5). Details of the processes used to identify genes with altered transcript levels as a fu […]


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CEBS institution(s)
ASRCFederal Vistronix, Morrisville, NC, USA; Division of the National Toxicology Program, National Institute of Environmental Health Sciences, Research Triangle Park, NC, USA
CEBS funding source(s)
ASRC Federal Vistronix under National Institute of Environmental Health Sciences (NIEHS) contracts ‘Support for Toxicological Data for the National Toxicology Program (NTP)’ (HHSN31620120054W and HHSN273201000063U GS06F0629Z)

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