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CES specifications


Unique identifier OMICS_23736
Name CES
Alternative name Combined Error Score
Software type Application/Script
Interface Command line interface
Restrictions to use None
Computer skills Advanced
Stability Stable
Source code URL https://gitlab.com/Carbonell/ces/repository/master/archive.tar.gz
Maintained Yes




No version available


  • person_outline Joaquin Dopazo
  • person_outline Jose Carbonnell-Caballero

Publication for Combined Error Score

CES citations


Reference genome assessment from a population scale perspective: an accurate profile of variability and noise

PMCID: 5870781
PMID: 28961772
DOI: 10.1093/bioinformatics/btx482

[…] a specific kind of noise is present at a given region. Due to this, we combine the set of empirical P-values obtained from all scores into a single and more accurate artifact estimator, that we call combined error score (CES).In order to define a robust estimator, the CES is computed by using the Fisher’s method for combining P-values (), where a combined score (10)x=−2∑q=1m  log  (pq), is assume […]


Revisiting the co existence of Attention Deficit/Hyperactivity Disorder and Chronic Tic Disorder in childhood—The case of colour discrimination, sustained attention and interference control

PLoS One
PMCID: 5464598
PMID: 28594866
DOI: 10.1371/journal.pone.0178866

[…] The following analysis is based on the speed-accuracy analysis, with age, IQ and Farnsworth-Munsell total error score (combined error score from both axes) initially entered as covariates; IQ was then dropped since it had no significant impact.This covariance analysis revealed better combined speed-accuracy performanc […]


Comparison of RefSeq protein coding regions in human and vertebrate genomes

BMC Genomics
PMCID: 3882889
PMID: 24063302
DOI: 10.1186/1471-2164-14-654

[…] utlier contig N50 values, the Pearson correlation coefficient was 0.88 for primates, 0.95 for rodents, 0.67 for mammals, and 0.87 for vertebrates (all p-values < 0.03). These results confirm that the combined “error” score may be valuable for estimating quality, especially by comparing scores between close species.We note that the number of core proteins in each species is only weakly correlated w […]


A Novel Method Testing the Ability to Imitate Composite Emotional Expressions Reveals an Association with Empathy

PLoS One
PMCID: 3633957
PMID: 23626756
DOI: 10.1371/journal.pone.0061941

[…] the relationship between EQ and emotion array more closely, we examined correlations between EQ and error scores for the two emotion arrays separately and combined. EQ correlated negatively with the combined error score (Pearson r = −0.420, p = 0.041, n = 24) and separately, EQ correlated negatively with the error score for the SAS array (r = −0.500, p = 0.013, n = 24) but not with the FHD array […]


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CES institution(s)
Computational Genomics, Principe Felipe Research Centre, Valencia, Spain; Estadıstica e investigacion Operativa, Universitat de Valencia, Burjassot, Spain; Clinical Bioinformatics Area, Fundacion Progreso y Salud, Hospital Virgen del Rocio, Sevilla, Spain; Functional Genomics Node (INB), Fundacion Progreso y Salud, Hospital Virgen del Rocio, Sevilla, Spain; Bioinformatics in Rare Diseases (BiER), Centro de Investigacion Biomedica en Red de Enfermedades Raras (CIBERER), Fundacion Progreso y Salud, Hospital Virgen del Rocio, Sevilla, Spain
CES funding source(s)
Supported by grants [BIO2014-57291-R] from the Spanish Ministry of Economy and Competitiveness and ‘Plataforma de Recursos Biomoleculares y Bioinformaticos’ [PT13/0001/0007] from ISCIII, both cofunded with European Regional Development Funds (ERDF); and [EU H2020-INFRADEV-1-2015-1 ELIXIR-EXCELERATE (ref. 676559)] and the Spanish Ministry of Economy and Competitiveness via research grant MTM2016-77501-P (jointly financed with the European Regional Development Fund).

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