Dataset features

Specifications


Application: Gene expression microarray analysis
Number of samples: 27
Release date: Sep 15 2017
Last update date: Sep 15 2017
Access: Public
Diseases: Tuberculosis
Chemicals: Iron
Computational protocol: MaxQuant, Andromeda
Dataset link Non-replicative persistence of M. tuberculosis under iron starvation

Experimental Protocol


M. tuberculosis was depleted of exogenous iron and pressed to use stored iron(Fe) at which point cells stop growing but remained viable for long time. Total RNA of iron depletion adapted Mtb (IDAM) at 1 day, 1 week and 2 weeks after cells have entered growth arrest was extracted and transcripts compared to those of cells subjected to Fe-depletion but then supplemented with Fe 24hr before RNA extraction. These cells are referred to as iron sufficient mycobacterium (ISM)

Repositories


GEO

GSE84554

BioProject

PRJNA329603

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Contact


G Rodriguez

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