cGRNB statistics

info info

Citations per year

info

Popular tool citations

chevron_left Gene regulatory network inference chevron_right
info

Tool usage distribution map

Tool usage distribution map
info info

Associated diseases

Associated diseases
Want to access the full stats & trends on this tool?

cGRNB specifications

Information


Unique identifier OMICS_11970
Name cGRNB
Alternative name combinatorial Gene Regulatory Networks Builder
Interface Web user interface
Restrictions to use None
Programming languages PHP, R
Computer skills Basic
Stability No
Maintained No

Maintainer


This tool is not available anymore.

Information


Unique identifier OMICS_11970
Name cGRNB
Alternative name combinatorial Gene Regulatory Networks Builder
Software type Package/Module
Interface Command line interface
Restrictions to use None
Operating system Unix/Linux, Mac OS, Windows
Programming languages R
Computer skills Advanced
Stability No
Maintained No

Versioning


No version available

Maintainer


This tool is not available anymore.

Publications for combinatorial Gene Regulatory Networks Builder

cGRNB citations

 (7)
library_books

Bioinformatics analysis of gene expression data for the identification of critical genes in breast invasive carcinoma

2017
PMCID: 5779935
PMID: 28990063
DOI: 10.3892/mmr.2017.7717

[…] analysis were performed using the reactome database (http://reactome.org/) ()., regulatory relationships between mirnas and target genes, and between tfs and target genes were downloaded from combinatorial gene regulatory networks builder (https://www.scbit.org/cgrnb/) (,). a total of 197,906 mirna-target gene relationships were acquired, which included 699 mature mirnas and 8,646 target […]

library_books

Screening of Critical Genes and MicroRNAs in Blood Samples of Patients with Ruptured Intracranial Aneurysms by Bioinformatic Analysis of Gene Expression Data

2017
PMCID: 5618721
PMID: 28930970
DOI: 10.12659/MSM.902953

[…] the degs in each enriched module were carried out for identifying overrepresented go terms and pathways using the david bioinformatics resources []. a p value <0.05 was set as the criterion., the combinatorial gene regulatory networks builder (cgrnb; http://www.scbit.org/cgrnb/) is a freely available web server to help biologists to model and analyze conditional combinatorial gene regulatory […]

library_books

Identification of hub genes and regulatory factors of glioblastoma multiforme subgroups by RNA seq data analysis

2016
PMCID: 5029949
PMID: 27572852
DOI: 10.3892/ijmm.2016.2717

[…] of a node reflects the number of the interacted proteins with this specific protein. hub nodes were deemed as the prominent nodes with high degrees., the combinatorial gene regulatory networks (cgrnb; http://www.scbit.org/cgrnb/) is a web server for the establishment of two major network modules such as mirna-perturbed gene expression (mpge) datasets and the parallel mirna/mrna expression […]

library_books

Screening of biomarkers for prediction of response to and prognosis after chemotherapy for breast cancers

2016
PMCID: 4861001
PMID: 27217777
DOI: 10.2147/OTT.S92350

[…] factors that significantly regulate the dcgs according to the targets enrichment density (ted) and targets dcl density (tdd) scores. the human gene regulatory relationships were collected from the cgrnb (combinatorial gene regulatory networks builder; http://www.scbit.org/cgrnb/) database, which contains 214 transcription factors and 16,831 target genes to form 210,637 pairs of regulatory […]

library_books

Integrative Analysis of Transcriptional Regulatory Network and Copy Number Variation in Intrahepatic Cholangiocarcinoma

2014
PMCID: 4045758
PMID: 24897108
DOI: 10.1371/journal.pone.0098653

[…] combined engineering () method to construct icc-specific trn (icc-trn). sequence-based tf-gene pairs were downloaded from our web platform for building combinatorial gene regulation networks (cgrnb, http://www.scbit.org/cgrnb/), which defines tf-gene pair as that tf's binding site should be located between upstream 1 kb and downstream 0.5 kb of transcription start sites . 203633 tf-gene […]

library_books

Reconstruction and Analysis of Transcription Factor–miRNA Co Regulatory Feed Forward Loops in Human Cancers Using Filter Wrapper Feature Selection

2013
PMCID: 3812136
PMID: 24205155
DOI: 10.1371/journal.pone.0078197

[…] types of regulatory interactions were investigated in this study: tf to mirna (tf-mirna), tf to gene (tf-gene), and mirna to gene (mirna-gene). we downloaded predicted tf-mirna interactions from cgrnb website with 11,599 regulatory pairs. to retrieve candidate tf-gene interactions, tf binding sites were first extracted from the tfbsconssites file from ucsc by following the procedure […]


Want to access the full list of citations?
cGRNB institution(s)
School of Life Sciences and Biotechnology, Shanghai Jiao Tong University, Shanhgai, China; Shanghai Center for Bioinformation Technology, Shanghai, China; Key Lab of Systems Biology, Shanghai Institutes for Biological Sciences, Chinese Academy of Sciences, Shanghai, China
cGRNB funding source(s)
The National key basic research program (funding numbers: 2011CB910204, 2012CB316501, 2011CB910200, 2010CB912702); Chinese Academy of Sciences (Innovation funding KSCX2-YW-R-112, KSCX2-EW-R-04); National Natural Science Foundation of China (31000380, 60970050, 31171268, 90913009)

cGRNB reviews

star_border star_border star_border star_border star_border
star star star star star

Be the first to review cGRNB